Incheon
National
University
Protein
Engineering
Lab
Research Field
Protein Engineering
Developing Next Generation Vector Platform for Therapeutic Protein Production
Aging
Aging control by the autophagy-mediated regulation of metabolism
Cancer Cell Biology
Investigating the relationship between aging and cancer
Summary of technique I [pdf]
Summary of technique II [pdf]
Summary of technique III [pdf]
Summary of technique IV [pdf]
Summary of technique V [pdf]
Summary of technique V [pdf]
Professor
Joon Tae Park Ph.D.
Associate Professor, Division of Life Sciences, Incheon National University
Johns Hopkins University School of Medicine Ph.D.
Seoul National University, Biological Science, M.S.
Seoul National University, Biology education, B.S.
e-mail: joontae.park@inu.ac.kr
Phone: +82-032-835-8841
+82-010-2239-2811
Address: 119 academy-ro, 5dong 514ho, Yeonsu-gu, , Incheon, 22012, Korea.
CURRICULUM VITAE: [pdf]
2004
Johns Hopkins School of Medicine
2013
Samsung Advanced Institute of Technology
2016
Samsung Bioepis
2017
Incheon National University
Current Member
Postdoctoral fellow:
Myeong Uk Kuk
CV: [pdf]
Project:
1) ROSA26 mediated Ab expression in CHO cells
2) B-Raf inhibitor in senescence reversal
Postdoctoral fellow:
Yoon Haeng Lee
CV: [pdf]
Project:
1) SB-based transposon system in CHO cells
2) HTS project
Ph.D. Degree Student:
Moon Kyoung So
CV:
Project:
1) Mechanisms by which hydrolysates benefit mammalian cell culture
Combined Undergraduate and Master Degree Student:
Jee hee Yoon
CV:
Project:
1) Skin rejuvenation project
Undergraduate Student:
Yu Jin Lee
CV:
Project:
1) Skin rejuvenation project
2024 Lab Homecoming day
2023 Graduation Party (Aug)
2023 Graduation Party (Feb)
2022 Lab Homecoming day
2021 KSBMB (생화학분자생물학회 국제학술대회) Best Research Award
2021 Teacher's day
2020 Graduation Party
2019 March
2019 Christmas Party
2018 ASK summer workshop
2018 Christmas Party
Previous Member
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Master Degree Student:
Jae Won Kim
CV: [pdf]
Current position:
(주)캔서롭
Master Degree Student:
Soo Young Hwang
CV: [pdf]
Current position:
(주)바이오노트
.jpg)
Master Degree Student:
HANEUR LEE
CV: [pdf]
Current position:
겐트대학교
Master Degree Student:
Eun Seon Song
CV: [pdf]
Current position:
Master Degree Student:
Ji Yun Park
CV: [pdf]
Current Position:
(주)SCM생명과학
Publication
Papers
[2024]
1. Song ES, Lee YH, So MK, Kuk MU, Park J, Yoon JH, Lee YJ, Kim D, So B, Byun Y, Kwon HW†, Park JT† (Mar 05, 2024) Establishment of a new promoter trapping vector using 2A peptide. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 10.1007/s12257-024-00096-4 [pdf]
2. Lim JS, Jeon EJ, Go HS, Kim H, Kim KY, Nguyen T, Lee DY, Kim KS, Pietrocola F, Hong SH, Lee SE, Kim K, Park TS, Choi D, Jeong Y, Park Jong, Kim HS, Min J, Kim YS, Park JT, Cho J, Lee G, Lee JH, Choy HE, Park SC, Lee C, Rhee JH, Serrano M, Cho KA (Jan 02, 2024) Mucosal TLR5 activation controls healthspan and longevity. Nature Communications 15(1):46 [PubMed][pdf]
3. Lee YH, Kuk MU, So MK, Park HJ, Song ES, Park J, Yoon JH, Kwon HW†, Choi J†, Park JT† (Nov 14, 2023) Polyporus ulleungus mycelia cultured in MEB medium produce metabolites with anticancer property. (†: co-corresponding author) Journal of Cancer (2022 Journal Impact factor: 4.478) 15(2):309-316 [PubMed][pdf]
[2023]
1. Song ES, So MK, Park HJ, Lee H, Lee YH, Kuk MU, Park J, Kwon HW, Choi J†, Park JT† (Jul 09, 2023) Chemical screening identifies the anticancer properties of Polyporous tuberaster. (†: co-corresponding author) Journal of Cancer (2022 Journal Impact factor: 4.478) 14(11): 2075-2084 [PubMed][pdf]
2. Lee YH*, Kuk MU*, So MK, Song ES, Lee H, Ahn S, Kwon HW†, Park JT†, Park SC† (Apr 15, 2023) Targeting Mitochondrial Oxidative Stress as a Strategy to Treat Aging and Age-Related Diseases. (*: co-first author, †: co-corresponding author) Antioxidants (2022 Journal Impact factor: 7.675) 12:934 [PubMed][pdf]
3. Lee H, Song ES, Lee YH, Park JY, Kuk MU, Kwon HW, Roh H†, Park JT† (Feb 07, 2023) A novel hybrid promoter capable of continuously producing proteins in high yield. (†: co-corresponding author) Biochemical and Biophysical Research Communications (2022 Journal Impact factor: 3.322) 650: 103-108 [PubMed][pdf]
4. Kuk MU, Lee H, Song ES, Lee YH, Park JY, Jeong S, Kwon HW, Byun Y†, Park SC†, Park JT† (Jan 16, 2023) Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence. (†: co-corresponding author) Experimental Gerontology (2022 Journal Impact factor: 4.253) 173:112091 [PubMed][pdf]
5. Lee YH, Kim M, Park HJ, Park JY, Song ES, Lee H, Ko G, Ahn S, Kwon HW, Byun Y, Kim C†, Choi J†, Park JT† (Jan 01, 2023) Chemical screening identifies the anticancer properties of Polyporous parvovarius. (†: co-corresponding author) Journal of Cancer (2022 Journal Impact factor: 4.478) 14(1):50-60 [PubMed][pdf]
[2022]
1. Park JY, Lee H, Song ES, Lee YH, Kuk MU, Ko G, Byun YJ†, Kwon HW†, Park JT† Improvement of Tol2 transposon system by modification of Tol2 transposase. (†: co-corresponding author) Biotechnology and Bioprocess Engineering (2022 Journal Impact factor: 2.836) 27(6): 987-994 [PubMed][pdf]
2. Choi S, Lee H, Lee M, Park JT, Heynderickx PM, Wu D, Depuydt S, Asselman J, Janssen C, Häder DP, Han T, Park J (Nov 05, 2022) A Ten-Minute Bioassay to Test Metal Toxicity with the Freshwater Flagellate Euglena agilis. Biology (2022 Journal Impact factor: 5.168) 11(11):1618 [PubMed][pdf]
3. Kuk MU, Ga YJ, Kim YJ, Park JY, Song ES, Lee H, Lee YH, Ko G, Kim JK, Yeh JY, Kwon HW†, Byun YJ†, Park JT† (Oct 24, 2022) Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3. (†: co-corresponding author) Animal Cells and Systems (2022 Journal Impact factor: 1.815) 26(6) 275–28 [PubMed][pdf]
4. Park JY, Lee H, Song ES, Lee YH, Kuk MU, Ko G, Kwon HW†, Byun YJ†, Park JT† (Oct 07, 2022) Restoration of lysosomal and mitochondrial function through p38 MAPK inhibition ameliorates senescence. (†: co-corresponding author) Rejuvenation Research (2022 Journal Impact factor: 4.663)
25(6):291-299 [PubMed][pdf]
5. Yang EJ, Park JH, Cho HJ, Hwang J, Woo S, Park CH, Kim SY, Park JT, Park SC, Hwang D, Lee Y (Jul 14, 2022) Co-inhibition of ATM and ROCK synergistically improves cell proliferation in replicative senescence by activating FOXM1 and E2F1. Commun Biol. 2022 5(1):702 [PubMed][pdf]
6. Lee YH, Park JY, Song ES, Lee H, Kuk MU, Joo JH, Roh H†, Park JT† (Jun 25, 2022) Improvement of Sleeping Beauty transposon system enabling efficient and stable protein production. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 27(3): 353-360 (2022 Journal Impact factor: 2.836) [PubMed][pdf]
7. Kuk MU, Park JY, Song ES, Lee H, Lee YH, Joo JH, Kwon HW†, Park JT† (May 24, 2022) Bacterial artificial chromosome-based protein expression platform using the Tol2 transposon system. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 27(3): 344-352 (2022 Journal Impact factor: 2.836) [PubMed][pdf]
8. Park JT, Oh S (Mar 03, 2022) The translational landscape as regulated by the RNA helicase DDX3. BMB Rep. 55(3): 125-135 (2021 Journal Impact factor: 4.16) [PubMed][pdf]
9. Lee YH, Choi D, Jang G, Park JY, Song ES, Lee H, Kuk MU, Joo JH, Ahn SK, Byun Y†, Park JT† (Jan 30, 2022) Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence. (†: co-corresponding author) Aging 14(2):678-707 (2020 Journal Impact factor: 5.682) [PubMed][pdf]
[2021]
1. Kuk MU, Lee YH, Kim JW, Hwang SY, Park JY, Song ES, Kwon HW, Oh S, Park JT (Dec 31, 2021) Rapid and Efficient BAC Recombineering: Gain & Loss Screening System. Biotechnology and Bioprocess Engineering 26(6): 1023-1033 (2020 Journal Impact factor: 2.213) [PubMed][pdf]
2. Lee YH, Park JY, Lee H, Song ES, Kuk MU, Joo JH, Oh S, Kwon HW†, Park JT†, Park SC† (Nov 03, 2021) Targeting mitochondrial metabolism as a strategy to treat senescence (†: co-corresponding author) Cells 10(11): 3003 (2021 Journal Impact factor: 6.600) [PubMed][pdf]
3. Kim JW, Lee YH, Kuk MU, Hwang SY, Kwon HW, Park JT (Oct 31, 2021) Cre/Lox-based RMCE for site-specific integration in CHO cells. Biotechnology and Bioprocess Engineering 26(5): 795-803 (2020 Journal Impact factor: 2.213) [PubMed][pdf]
4. Hwang SY, Lee YH, Kuk MU, Kim JW, Oh S, Park JT (Oct 31, 2021) Improvement of Tol2 transposon system enabling efficient protein production in CHO cells. Biotechnology and Bioprocess Engineering 26(5): 767-775 (2020 Journal Impact factor: 2.213) [PubMed][pdf]
5. Lee HJ, Stephen Depuydt, Shin KS, Choi SY, Kim GH, Lee YH, Park JT, Han TJ, Park JH (Jul 02, 2021), Assessment of various toxicity endpoints in duckweed (Lemna minor) at the physiological, biochemical, and molecular levels as a measure of diuron stress. Biology. 10(7):684 [PubMed][pdf]
6. Park JH, Ryu SJ, Kim BJ, Cho HJ, Park CH, Choi HJC, Jang EJ, Yang EJ, Hwang JA, Woo SH, Lee JH, Park JH, Choi KM, Kwon YY, Lee CK, Park JT, Cho SC, Lee YI, Lee SB, Han JA, Cho KA, Kim MS, Hwang D, Lee YS, Park SC (Jun 29, 2021) Disruption of nucleocytoplasmic trafficking as a cellular senescence driver. Exp Mol Med 53:1092-1108 [PubMed][pdf]
7. Kuk MU, Lee YH, Kim JW, Hwang SY, Park JT†, Park SC† (Feb 17, 2021) Potential Treatment of Lysosomal Storage Disease Through Modulation of the Mitochondrial–Lysosomal Axis. (†: co-corresponding author) Cells. 10(2): 420. (2020 Journal Impact factor: 4.829) [PubMed][pdf]
8. Song N, Jeong DY, Tu TH, Park BS, Yang HR, Kim YJ, Kim JK, Park JT, Yeh JY, Yang S, Kim JG (Feb 04, 2021) Adiponectin Controls Nutrient Availability in Hypothalamic Astrocytes. Int J Mol Sci. 22(4):1587 [PubMed][pdf]
9. Park JH, Lee HJ, Choi SY, Pandey LK, Depuydt S, Saeger JD, Park JT, Han TJ (Jan 04, 2021) Extracts of red seaweed, Pyropia yezoensis, inhibit melanogenesis but stimulate collagen synthesis. Journal of Applied Phycology. 33:653–662 [PubMed][pdf]
[2020]
1. Hwang SY, Kuk MU, Kim JW, Lee YH, Lee YS, Choy HE, Park SC, Park JT (Nov 01, 2020) ATM mediated-p53 signaling pathway forms a novel axis for senescence control. Mitochondrion. DOI: 10.1016/j.mito.2020.09.002 (2020 Journal Impact factor: 3.430) [PubMed] [pdf]
2. Lim JS, Lee DY, Kim HS, Park SC, Park JT, Kim HS, Oh WK, Cho KA (Dec 01, 2020) Identification of a novel senomorphic agent, avenanthramide C, via the suppression of the senescence-associated secretory phenotype. Mech Ageing Dev. 192:111355 [PubMed] [pdf]
3. Cho HJ, Yang EJ, Park JT, Kim JR, Kim EC, Jung KJ, Park SC, Lee YS (May 07, 2020) Identification of SYK inhibitor, R406 as a novel senolytic agent. Aging 12(9):8221-8240 (2019 Journal Impact factor: 4.831)[PubMed] [pdf]
[2019]
1. Kim JW*, Kuk MU*, Choi HE, Park SC†, Park JT† (Oct 15, 2019) Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. (*: co-first author, †: co-corresponding author) Exp Gerontol. 126: 110691 (2019 Journal Impact factor: 3.08) [PubMed] [pdf]
2. Oh S, Park JT (May 10, 2019) Zebrafish model of KRAS-initiated pancreatic endocrine tumor. Animal Cells and Systems. 23(3):209-218 (2019 Journal Impact factor: 0.549) [PubMed] [pdf]
3. Kuk MU*, Kim JW*, Lee YS, Cho KA, Park JT†, Park SC† (Mar 31, 2019) Alleviation of senescence via ATM inhibition in accelerated aging models. (*: co-first author, †: co-corresponding author) Mol Cells. 42(3):210-217 (2019 Journal Impact factor: 3.533) [PubMed] [pdf]
4. Kang SU, Park JT (Feb 01, 2019) Functional evaluation of alternative splicing in the FAM190A gene. Genes & Genomics. 41(2):193-199 (2019 Journal Impact factor: 1.188) [PubMed] [pdf]
[2018]
1. Park JT, Lee YS, Park SC (Nov 25, 2018) Quantification of Autophagy During Senescence. Methods Mol Biol. 1896:149-157 (2019 Journal Impact factor: 0.91) [PubMed] [pdf]
2. Park JT, Leach SD (Oct 08, 2018) Zebrafish model of KRAS-initiated pancreatic cancer. Animal Cells and Systems. 22(6): 353-359 (2019 Journal Impact factor: 0.549) [PubMed] [pdf]
3. Park JT, Lee YS, Cho KA, Park SC (Nov 01, 2018) Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence. Ageing Res Rev. 47:176-182 (2019 Journal Impact factor: 10.39) [PubMed] [pdf]
4. Park JT, Kang HT, Park CH, Lee YS, Cho KA, Park SC (Jun 01, 2018) A crucial role of ROCK for alleviation of senescence-associated phenotype. Exp Gerontol. 106:8-15 (2019 Journal Impact factor: 3.08) [PubMed] [pdf]
[2017]
1. Kang HT*, Park JT*†, Choi K*, Choi HJ, Jung CW, Lee YS†, ParkSC† (Mar 27, 2017). Chemical screening identifies ATM as a target for alleviating senescence (As co-first and co-corresponding author) Nat Chem Biol. 13:616-623. (2019 Journal Impact factor: 12.154) [PubMed] [pdf]
2. Kang HT*, Park JT*†, Choi K, Choi HJ, Jung CW, Kim GR, Lee YS†, ParkSC† (Jun 01, 2017). Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome (As co-first and co-corresponding author) Aging Cell 16(3):541-550. (2019 Journal Impact factor: 7.346) [PubMed] [pdf]
[2016]
1. Jung JG, Shih IM, Park JT, Gerry E, Kim TH, Ayhan A, Handschuh K, Davidson B, Nickles Fader A, Selleri L, Wang TL (Nov 01, 2016). Ovarian cancer chemoresistance relies on the stem cell reprogramming factor PBX1. Cancer Res. 76(21):6351-6361. [PubMed] [pdf]
[2015]
1. Park JT, Johnson N, Liu S, Levesque M, Wang YJ, Ho H, Huso D, Maitra A, Parsons MJ, Prescott JD, Leach SD (May 21, 2015). Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey. Oncogene 34(21): 2801–2806. (2019 Journal Impact factor: 6.634) [PubMed] [pdf]
2. Kim MS, Jo S, Park JT, Shin HY, Kim SS, Gurel O, Park SC (Aug 31, 2015). Method To Purify and Analyze Heterogeneous Senescent Cell Populations Using a Microfluidic Filter with Uniform Fluidic Profile. Anal Chem. 87(19):9584-8. [PubMed] [pdf]
3. Wang YJ, Park JT, Parsons MJ, Leach SD (Jun 01, 2015). Fate mapping of ptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish. Dev Dyn. 244:724-35 [PubMed] [pdf]
[2013]
1. Park JT, Leach SD. (Dec 31, 2013) TAILOR (Transgene Activation and Inactivation with LOx and Rox). PLOS ONE 8: e85218 (2019 Journal Impact factor: 2.776) [PubMed] [pdf]
2. Pashos E, Park JT, Leach S, Fisher S (Sep 15, 2013). Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish. Dev Biol. 381:471-481 [PubMed] [pdf]
3. Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng CX, Ye Z, Jang YY (Jun 01, 2013). Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology. 57(6): 2458–2468 [PubMed] [pdf]
[2010]
1. Park JT, Chen X, Trope CG,Davidson B, Shih IeM, Wang TL (Sep 01, 2010). Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin. Am J Pathol. 177(3):1087-94 (2019 Journal Impact factor: 3.762) [PubMed] [pdf]
[2008]
1. Park JT, Shih IeM, Wang TL (Nov 01, 2008). Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. Cancer Res 68(21): 8852-8860 (2019 Journal Impact factor: 8.378) [PubMed] [pdf]
2. Choi JH, Park JT, Davidson B, Morin PJ, Shih IeM, Wang TL (Jul 15, 2008). Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Res. 68(14):5716-23. [PubMed] [pdf]
[2006]
1. Park JT, Li M, Nakayama K, Mao TL, Davidson B, Zhang Z, Kurman RJ, Eberhart CG, Shih IeM, Wang TL (Jun 15, 2006). Notch3 gene amplification in ovarian cancer. Cancer Res. 66(12):6312-8 (2019 Journal Impact factor: 8.378) [PubMed] [pdf]
[2005]
1. Choi KS, Park JT, Dumler JS (Dec 01, 2005) Anaplasma phagocytophilum delay of neutrophil apoptosis through the p38 mitogen-activated protein kinase signal pathway. Infect Immun. 73(12):8209-18. [PubMed] [pdf]
[2002]
1. Park JT, Jung YE, Ahn TI (Dec 01, 2002) Changes in profiles of major proteins in encysting Acanthamoeba castellanii Korean J. Biol. Sci. 6: 341-347 [PubMed] [pdf]
Book Chapters
[2009]
1. Park JT, Shih IeM, Wang TL (2009) Targeting Notch Signaling Pathway in Cancer Stem Cell. Cancer Stem Cells Cambridge University Press; 128-138 [pdf]
Book Translation
[2022]
1. 캠벨 생명과학, 12판 (2022). ㈜바이오사이언스 출판 [LINK]
2. 캠벨 생명과학의 이해, 2nd edition (2022). ㈜바이오사이언스 출판 [LINK]
[2021]
1.캠벨 생명과학 포커스, 3판 (2021). ㈜바이오사이언스 출판 [LINK]
[2019]
1. 캠벨 생명과학, 11판 (2019). ㈜바이오사이언스 출판 [LINK]
Patent
International Patent (Registration)
[2020]
1. Park JT, Lee KJ, Lim JS, Lim HT, Heo YJ, Lee JS, Min HS (Nov 05, 2020), Process for reducing undesirable by-product in cell culture, AU2017349343B2 (Registration) [pdf]
[2018]
1. Choi K*, Park JT, Kang HT (Apr 24, 2018), Composition for reducing senescence of cell or subject comprising smurf2 inhibitor and use thereof, US9951336B2 (Registration) [pdf]
2. Park JT, Kang HT, Jung CW, Choi K, Park SC, Choi HJ (Apr 17, 2018), COMPOSITION FOR REDUCING CELL SENESCENCE COMPRISING RHO-KINASE INHIBITOR AND USE THEREOF, US9943525B2 (Registration) [pdf]
[2017]
1. Jung CW*, Park JT*, Kang HT, Park SC, Choi HJ, Choi K (Sep 26, 2017), COMPOSITION INCLUDING ATM INHIBITOR FOR REDUCING CELLULAR SENESCENCE AND USE OF THE COMPOSITION, US9770451B2 (Registration) [pdf]
2. Keum JW*, Park JT*, Jung CW, Park SC, Lee YS (Sep 19, 2017), COMPOSITION FOR REDUCING SENESCENCE OF CELL OR SUBJECT INCLUDING BRAF INHIBITOR AND USE THEREOF, US9763923B2 (Registration) [pdf]
Korean Patent (Registration)
[2022]
1. 국명욱, 박준태 (Apr 04, 2022), 박테리아 인공 염색체 재조합 스크리닝 방법, 10-2384173 (Registration) [pdf]
2. 이윤행, 박준태 (Feb 16, 2022), 개선된 슬리핑 뷰티 트랜스포존 시스템 및 이를 이용한 유전자 전위 방법, 10-2365768 (Registration) [pdf]
3. 황수영, 박준태 (Feb 09, 2022), CHO 세포에 전이 유전자를 통합하기 위한 방법, 10-2362878 (Registration) [pdf]
4. 최고봉, 박준태, 강현태 (Feb 03, 2022) Smurf2의 저해제를 포함하는 세포 또는 개체의 노화를 감소시키기 위한 조성물 및 그의 용도, 10-2360028 (Registration) [pdf]
5. 국명욱, 박준태 (Jan 10, 2022), Tol2 트랜스포존 시스템을 포함하는 인공 염색체 및 이를 이용한 단백질 생산 방법, 10-2350981 (Registration) [pdf]
[2021]
1. 김재원, 박준태 (Nov 30, 2021), Fer1L4 유전자에 부위-특이적 통합된 RMCE 랜딩 패드를 포함하는 CHO 세포, 10-2335242 (Registration) [pdf]
2. 박준태, 강현태, 정철원, 최고봉, 박상철, 최효제 (Jul 06, 2021), 로-키나제 저해제를 포함하는 세포의 노화를 감소시키기 위한 조성물 및 그의 용도, 10-2276424 (Registration) [pdf]
International Patent (Filling)
[2022]
1. Lee YH, Byun YJ, Choi DY, Park JT (Feb 07, 2022), PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING AGING OR AGE-RELATED DISEASES, 17/633,576 (Filling) [pdf]
[2021]
1. Lee YH, Byun YJ, Choi DY, Park JT (Jul 23, 2021), PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING AGING OR AGE-RELATED DISEASES, PCT/KR2021/009592 (Filling) [pdf]
2. Kuk MU, Park JT (Feb 19, 2021), ARTIFICIAL CHROMOSOME COMPRISING TOL2 TRANSPOSON SYSTEM AND PROTEIN PRODUCTION METHOD USING SAME, PCT/KR2021/002138 (Filling) [pdf]
[2020]
1. Lee YH, Park JT (Dec 07, 2020), DEVELOPED SLEEPING BEAUTY TRANSPOSON SYSTEM AND METHOD OF GENE TRANSPOSITION USING THEREOF, PCT/KR2020/017709 (Filling) [pdf]
2. Kuk MU, Park JT(Aug 27, 2020), SCREENING METHOD OF BACTERIAL ARTIFICIAL CHROMOSOMES RECOMBINEERING, PCT/KR2020/011464 (Filling) [pdf]
Korean Patent (Filling)
[2024]
1. 이유진, 송은선, 권형욱, 변영주, 이기용, 박준태 (May 03, 2024), 디히드로악테오사이드를 유효성분으로 포함하는 항노화 조성물, 10-2024-0059125 (Filling) [pdf]
2. 윤지희, 권형욱, 변영주, 이기용, 박준태 (May 02, 2024), 비티신 B를 유효성분으로 포함하는 항노화 조성물, 10-2024-0058770 (Filling) [pdf]
3. 국명욱, 김두열, 권형욱, 변영주, 이기용, 박준태 (Apr 30, 2024), 사우치논을 유효성분으로 포함하는 항노화 조성물, 10-2024-0058049 (Filling) [pdf]
4. 박지호, 권형욱, 변영주, 이기용, 박준태 (Apr 30, 2024), ε-비니페린을 유효성분으로 포함하는 항노화 조성물, 10-2024-0057851 (Filling) [pdf]
5. 이윤행, 소병현,권형욱, 변영주, 이기용, 박준태 (Apr 29, 2024), 이소샤프토사이드를 유효성분으로 포함하는 항노화 조성물, 10-2024-0056806 (Filling) [pdf]
6. 국명욱, 권형욱, 변영주, 박준태 (Feb 16, 2024), 결손된 iMAR 유전자를 포함하는 목적 단백질 발현 카세트 및 벡터 및 이를 포함하는 형질전환 세포, 10-2024-0022827 (Filling) [pdf]
[2023]
1. 이윤행, 권형욱, 변영주, 박준태 (Aug 29, 2023), 옥사졸 유사체를 유효성분으로 포함하는 항노화 조성물, 10-2023-0113722 (Filling) [pdf]
2. 이하늘, 변영주, 박준태 (Aug 22, 2023), 신규한 프로모터, 10-2023-0110153 (Filling) [pdf]
3. 국명욱, 권형욱, 박준태 (Mar 21, 2023), ROSA26 박테리아 인공염색체 내인성 프로모터, 10-2023-0036503 (Filling) [pdf]
4. 이윤행, 박지윤, 한태준, 박지혜, 이호준, 박준태 (Mar 13, 2023) 민물고기 세포의 증식 특성을 이용한 생태독성 평가방법, 10-2023-003316 (Filling) [pdf]
[2022]
1. 국명욱, 박지윤, 권형욱, 변영주, 박준태 (Nov 18, 2022), 콕사키바이러스 B3 감염 치료 또는 예방용 조성물, 10-2022-0155706 (Filling) [pdf]
2. 송은선, 권형욱, 변영주, 박준태 (Aug 11, 2022), RMCE 랜딩패드, 10-2022-0100663 (Filling) [pdf]
3. 이하늘, 권형욱, 변영주, 박준태 (Aug 05, 2022), 하이브리드 프로모터, 10-2022-0098167 (Filling) [pdf]
4. 박지윤, 권형욱, 변영주, 박준태 (Jul 29, 2022), MAPK 저해제를 포함하는 리소좀 활성화 방법, 10-2022-0095059 (Filling) [pdf]
5. 국명욱, 이윤행, 권형욱, 변영주, 박준태 (Jul 29, 2022), AKT 저해제를 포함하는 미토파지 활성화 방법, 10-2022-0095033 (Filling) [pdf]
6. 송은선, 최재혁, 임영운, 박준태 (Feb 24, 2022), 항암 활성을 가지는 폴리포루스 튜버래스터 균주 배양방법, 10-2022-0024281 (Filling) [pdf]
7. 이윤행, 최재혁, 김창무, 김민경, 안초롱, 유영현, 지원재, 임영운, 박준태 (Feb 14, 2022), 항암 활성을 가지는 폴리포루스 울릉구스 균주, 10-2022-0018938 (Filling) [pdf]
8. 박지윤, 박준태 (Jan 28, 2022), 신규한 트랜스포사제 및 이를 이용한 트랜스포존 시스템, 10-2022-0013246 (Filling) [pdf]
[2021]
1. 이윤행, 최재혁, 김창무, 김민경, 안초롱, 유영현, 지원재, 박준태 (Nov 15, 2021), 항암 활성을 가지는 폴리포루스 파보바리우스(Polyporus parvovarius) 균주, 10-2021-0156407 (Filling) [pdf]
2. 이윤행, 변영주, 최도영, 박준태 (Feb 18, 2021), 세포노화 관련 질병의 예방 또는 치료용 약학적 조성물, 10-2021-0022067 (Filling) [pdf]
[2016]
1. 박준태, 이경주, 임주송, 임형택, 허윤정, 이재선, 민호성 (Oct 31, 2016) 세포 배양 배지에서 원치 않는 배양 부산물을 감소시키는 공정, 10-2016-0143427 (Filling) [pdf]
Courses
[2022]
Protein Engineering
Main Teaching Material
Proteins: Structure and Function
by David Whitford
Chapter 1. An introduction to protein structure and function [link]
Chapter 2. Amino acids: the building blocks of proteins [link]
Chapter 3. The three-dimensional structure of proteins [link]
Chapter 1 & 2 & 3 summary by ZOOM [link]
Chapter 4. The structure and function of fibrous proteins [link]
Chapter 5. The structure and function of membrane proteins [link]
Chapter 4 & 5 summary by ZOOM [link]
Chapter 6. The diversity of proteins [link]
Chapter 7. Enzyme kinetics, structure, function and catalysis [link]
Chapter 6 & 7 summary by ZOOM [link]
Chapter 8. Protein synthesis, processing and turnover [link]
Chapter 9. Protein expression, purification and characterization [link]
Chapter 11. Protein folding in vivo and in vitro [link]
Chapter 8 & 9 & 11 summary by ZOOM [link]
[2022]
Genetics
Main Teaching Material
Genetics: A Conceptual Approach, 6th Edition
by Benjamin A. Pierce
Chapter 1. Introduction to Genetics [link]
Chapter 2. Chromosomes and Cellular Reproduction [link]
Chapter 3. Basic Principles of Heredity [link]
Chapter 4. Sex Determination and Sex-Linked Characteristics [link]
Chapter 1 & 2 & 3 & 4 summary by ZOOM [link]
Chapter 5. Extensions and Modifications of Basic Principles [link]
Chapter 6. Pedigree Analysis, Applications, and Genetic Testing [link]
Chapter 5 & 6 summary by ZOOM [link]
Chapter 7. Linkage, Recombination, and Eukaryotic Gene Mapping [link]
Chapter 8. Chromosome Variation [link]
Chapter 7 & 8 summary by ZOOM [link]
Chapter 9. Bacterial and Viral Genetic Systems [link]
Chapter 10. DNA: The Chemical Nature of the Gene [link]
Chapter 11. Chromosome Structure and Organelle DNA [link]
Chapter 9 & 10 & 11 summary by ZOOM [link]
[2022]
Epigenetics
Main Teaching Material
Introduction to Epigenetics
by Dae Yup Lee
Chapter 1. Overview about Epigenetics [link]
Chapter 2. Epigenetics in Saccharomyces cerevisiae [link]
Chapter 1 & 2 summary by ZOOM [link]
Chapter 3. Epigenetics in Schizosaccharomyces pombe [link]
Chapter 4. Epigenetics in Fruit Fly [link]
Chapter 5. Epigenetics in Mammals [link]
Chapter 3 & 4 & 5 summary by ZOOM [link]
Chapter 6. Mono-allelic Expression [link]
Chapter 7. RNA-directed DNA Methylation(RdDM) in Plant [link]
Chapter 6 & 7 summary by ZOOM [link]
Chapter 8. Histone Variant and Epigenetics [link]
Chapter 9. Histone Ubiquitylation [link]
Chapter 10. Histone Acetylation/Deacetylation [link]
Chapter 8 & 9 & 10 summary by ZOOM [link]
[2022]
Biology foundation(1)
Main Teaching Material
Life : the science of biology 12th edition
By David M. Hillis, H. Craig Heller, Sally D. Hacker,
David W. Hall, Marta J. Laskowski, David E. Sadava
Chapter 1. Studying Life
Chapter 2. Small Molecules and the Chemistry of Life [link]
Chapter 3. Proteins, Carbohydrates, and Lipids [link]
Chapter 4. Nucleic Acids and the Origin of Life
Chapter 5. Cells: The Working Units of Life [link]
Chapter 6. Cell Membranes [link]
Chapter 7. Cell Communication and Multicellularity [link]
Chapter 8. Energy, Enzymes, and Metabolism [link]
Chapter 9. Pathways that Harvest Chemical Energy [link]
Chapter 10. Photosynthesis: Energy from Sunlight [link]
Chapter 11. The Cell Cycle and Cell Division [link]
Chapter 12. Inheritance, Genes, and Chromosomes [link]
Chapter 13. DNA and Its Role in Heredity [link]
Chapter 14. From DNA to Protein: Gene Expression [link]
Chapter 15. Gene Mutation and Molecular Medicine [link]
Chapter 16. Regulation of Gene Expression [link]
Chapter 17. Genomes [link]
Chapter 18. Recombinant DNA and Biotechnology [link]
Chapter 19. Processes of Evolution [link]
Chapter 20. Reconstructing and Using Phylogenies [link]
Chapter 21. Evolution of Genes and Genomes [link]
Chapter 22. Speciation [link]
Chapter 23. The History of Life on Earth [link]
Chapter 24. Bacteria, Archaea, and Viruses [link]
