Protein

Engineering

Lab

국내 / 연구실 소개 - 생화학분자생물학회

Research Field

Protein Engineering

Developing Next Generation Vector Platform for Therapeutic Protein Production

Aging

Aging control by the autophagy-mediated regulation of metabolism

Cancer Cell Biology

Investigating the relationship between aging and cancer

Summary of technique I [pdf]

Summary of technique II [pdf]

Summary of technique III [pdf]

Summary of technique IV [pdf]

Summary of technique V [pdf]

Summary of technique V [pdf]

서비스

Professor

Joon Tae Park Ph.D.

Professor, Division of Life Sciences, Incheon National University

Johns Hopkins University School of Medicine Ph.D.
Seoul National University, Biological Science, M.S.

Seoul National University, Biology education, B.S.

e-mail: joontae.park@inu.ac.kr

Phone: +82-032-835-8841

Address: 265 Harmony-ro, R&D COMPLEX 305ho, Yeonsu-gu, Incheon, 22014, Republic of Korea.

CURRICULUM VITAE: [pdf]

소개

2004

Johns Hopkins School of Medicine

2013

Samsung Advanced Institute of Technology

2016

Samsung Bioepis

2017

Incheon National University

프로젝트

Current Member

Combined Master's and Ph.D. Degree Student:
Jiho Park
CV: [pdf]
Project:
1) Skin rejuvenation project
(KB3407, KB2779)

Master Degree Student:
Yu Jin Lee
CV: [pdf]
Project:
1) Skin rejuvenation project

Master Degree Student:
Minseon Kim
CV: [pdf]
Project:
1) Skin rejuvenation project
2) Ecotoxicity Project

Undergraduate Student:
JIHYUN SONG
CV: [pdf]
Project:
1) Skin rejuvenation project

Undergraduate Student:
Se Hui Lim
CV: [pdf]
Project:
1) Skin rejuvenation project

Undergraduate Student:
Hanna Lee
CV:
Project:
1) Skin rejuvenation project

2026 송은선 석사 입사 축하

2026 Lab dinner at 배다리

2025 Lab member

2025 이윤행 박사 입사 축하

2025 이하늘 석사 입사 축하

2025 김두열 석사 입사 축하

2025 국명욱 박사 입사 축하

2025 소병현 석사 입사 축하

2024 Lab Homecoming day

2023 Graduation Party (Aug)

2023 Graduation Party (Feb)

2022 Lab Homecoming day

2021 KSBMB (생화학분자생물학회 국제학술대회) Best Research Award

https://www.ksbmb.or.kr/html/?pmode=webzine&smode=viewDetail&id=202106&menu=907&seq=35294

2021 Teacher's day

2019 March

2020 Graduation Party

2019 Christmas Party

2018 ASK summer workshop

2018 Christmas Party

Previous Member

Number of post-doc graduates: 2

Number of Ph.D. degree graduates: 4

Number of Master degree graduates: 10

Jae Won Kim
Master Degree: Feb 2021
CV: [pdf]
Current position:
(주)디엑스앤브이엑스(Dx&Vx)

Soo Young Hwang
Master Degree: Feb 2021
CV: [pdf]
Current position:
(주)바이오노트

Eun Seon Song
Master Degree: Feb 2024
CV: [pdf]
Current position:
한국과학기술연구원(KIST)
정규직 연구원

HANEUR LEE
Master Degree: Aug 2023
CV: [pdf]
Current position:
인천광역시 보건연구사

Yoon Haeng Lee
Master Degree: Feb 2022
Ph.D. Degree: Feb 2024
Post doc: Nov 2025
CV: [pdf]
Current position:
대웅제약 선임연구원

Duyeol Kim
Master Degree: Feb 2026
CV: [pdf]
Current position:
(주)라피끄 연구원

Ki Sik Shin
Ph.D. Degree: Feb 2022
CV:
Current position:
국립환경과학원 연구관

Moon Kyoung So
Ph.D. Degree: Aug 2024
CV: [pdf]
Current position:
Thermo Fisher Scientific 이사

Byeonghyeon So
Master Degree: Feb 2026
CV: [pdf]
Current position:
한국화학융합시험연구원
연구원

Ji Yun Park
Master Degree: Feb 2023
CV: [pdf]
Current Position:
(주)SCM생명과학

Myeong Uk Kuk
Master Degree: Feb 2020
Ph.D. Degree: Feb 2024
Post doc: Dec 2024
CV: [pdf]
Current position:
엣진(Edgene) 선임연구원

Jee hee Yoon
Master Degree: Aug 2026
CV: [pdf]
Current position:
취업 준비 중

제휴사

Publication

기술이전

[2025]

1.세포 노화 및 대사 기능 회복 효능을 갖는 후박나무 유래 역노화 조성물 (10-2024-0142926)외 4건 (현대바이오랜드), (선급기술료: 천만원, 경상기술료: 연 매출액의 1%) (Oct 15, 2025) [pdf]

Papers

[2026]

1. Kim M, Lee KS, Yoon JH, Park JH, Lee YJ, Song J, Kwon HW, Byun Y†, Lee KY †, Park JT† (Aug 17, 2026) Formononetin attenuates cellular senescence through a FOS-mediated mechanism. (†: co-corresponding author) Biogerontology 27(5): 144 (2026 Journal Impact factor: 5.3) [PubMed][pdf]

2. Lee YJ*, Yoon JH*, Lim H, Song ES, Park JH, Kim D, Yang J, So MK, Kim M, Song J, Lim S, Kwon HW, Byun Y†, Park JT† (Aug 12, 2026) A pyrazole-based small molecule, KB3409, restores mitochondrial function via VCP activation and RCN2-dependent Ca²⁺ regulation. (*: co-first author, †: co-corresponding author) Antioxidants 15(8): 1006 (2025 Journal Impact factor: 8.2) [PubMed][pdf]

3. Yoon JH*, Kim YH*, Kim M*, Jeong EY, Lee YH, Park JH, Lee YJ, Lee SH, Kim HY, Kang HM, Kwon HW, Byun Y, Shin SS†, Park JT† (Mar 10, 2026) 2-methoxystypandrone from Polygonum cuspidatum rejuvenates senescence by reducing mitochondrial ROS. (*: co-first author, †: co-corresponding author) Antioxidants 15(3): 357 (2025 Journal Impact factor: 8.2) [PubMed][pdf]

4. Yoon JH*, Lee YH*, Oh S*, Lee KS, Park JH, Lee YJ, So B, Kim D, Kim M, Kwon HW, Byun Y†, Lee KY†, Park JT† (Jan 21, 2026) Vitisin B rejuvenates senescence via WBP2NL regulation. (*: co-first author, †: co-corresponding author) Mechanisms of Ageing and Development 230: 112159 (2024 Journal Impact factor: 5.1) [PubMed][pdf]

5. Lee YH*, Jeong EY*, Kim YH*, Oh S*. Yoon JH, Park JH, Lee YJ, Kim D, So B, Kim M, Kim SY, Kwon HW, Byun Y†, Shin SS†, Park JT† (Jan 15, 2026) Liquid Extract from the bark of Magnolia officinalis Rejuvenates Skin Aging Through Mitochondrial ROS Reduction. (*: co-first author, †: co-corresponding author) Cosmetics 13: 22 (2024 Journal Impact factor: 3.2) [PubMed][pdf]

[2025]

1. Kim M*, Park JH*, So B, Lee H, Yoon JH, Lee YJ, Kim D, Kwon HW, Park J, Han T, Oh S†, Lee YH†, Park JT† (Oct 29, 2025) Rapid ecotoxicity and genotoxicity assessment using Macropodus ocellatus cells . (*: co-first author, †: co-corresponding author) Toxicological Research DOI: 10.1007/s43188-025-00325-9 (2024 Journal Impact factor: 2.3) [PubMed][pdf]

2. Shannonhouse J, Son H, Zhang Y, Kim E, Han D, Gomez R, Park JT, and Kim YS (Aug 1, 2025) In Vivo Calcium Imaging of Neuronal Ensembles in Networks of Primary Sensory Neurons in Intact Trigeminal Ganglia. J Vis Exp 222: e68284 (2024 Journal Impact factor: 2.3) [PubMed][pdf]

3. Shannonhouse J, Zhang Y, Son H, Kim E, Han D, Park JT, Kim YS (Aug 14, 2025) Lessons from the use of in vivo cellular calcium imaging in primary sensory neurons and spinal cord. Neuroscientist 31(6): 591-610 (2024 Journal Impact factor: 3.9) [PubMed][pdf]

4. Park JH*, Lee YH*, Lee KS, Lee YJ, Yoon JH, So B, Kim D, Kim M, Kwon HW, Byun Y, Lee KY†, Park JT† (Aug 22, 2025) ε-Viniferin Rejuvenates Senescence via RGS16 Regulation: In Vitro Evidence. (*: co-first author, †: co-corresponding author) Pharmaceutics 18(9): 1254 (2024 Journal Impact factor: 5.5) [PubMed][pdf]

5. Kim E, Son H, Zhang Y, Shannonhouse J, Gomez R, Han D, Park JT, Kim ST, Amarista Fe, Perez D, Ellis E, and Kim YS (May 31, 2025) BoNT injection in TMJ alleviates TMD pain in FMO-induced TMD mouse model. Journal of Neuroscience 45(41): e2035242025 (2024 Journal Impact factor: 3.9) [PubMed][pdf]

6. Zhang Y, Shannonhouse J, Son H, Park JT, Kim YS (May 31, 2025) Regulatory Action of Calcium and Calcium Channels in Pain Pathways. Int J Biol Sci 21(8):3726-3739 (2024 Journal Impact factor: 10.1)[PubMed][pdf]

7. Lee YJ*, Song ES*, Lee YH, Lee KS, So B, Park JH, Yoon JH, Kim D, Kim M, Kwon HW, Byun Y†, Lee KY†, Park JT† (Jun 02, 2025) Dehydroacteoside rejuvenates senescence via TVP23C-CDRT4 regulation. (*: co-first author, †: co-corresponding author) Experimental Gerontology 207:112800 (2024 Journal Impact factor: 3.3) [PubMed][pdf]

8. Park JH*, Jeong EY*, Kim YH*, Cha SY, Kim HY, Nam YK, Park JS, Kim Sy, Lee YJ, Yoon JH, So B, Kim D, Kim M, Byun Y, Lee YH†, Shin SS†, Park JT† (Apr 21, 2025) Epigallocatechin gallate in Camellia sinensis ameliorates skin aging by reducing 2 mitochondrial ROS production. (*: co-first author, †: co-corresponding author) Pharmaceutics 18(5): 612 (2024 Journal Impact factor: 4.3) [PubMed][pdf]

9. Lee YH*, Lim H*, Kim G, Jang G, Kuk MU, Park JH, Yoon JH, Lee YJ, Kim D, So B, Kim M, Kwon HW, Byun Y†, Park JT† (Apr 16, 2025) Elucidating the role and mechanism of alpha-enolase in senescent amelioration via metabolic reprogramming. (*: co-first author, †: co-corresponding author) Cell proliferation 2025; 0:e70049 (2024 Journal Impact factor: 5.9) [PubMed][pdf]

10. So B*, Park JH*, Kim MS, Lee H, Yoon JH, Lee YJ, Kim D, Kwon HW, Park J, Han T, Lee YH†, Park JT† (Apr 03, 2025) Rapid and Accurate Genotoxicity Assessment Using the Neutral Comet Assay in Cyprinus carpio Cells. (*: co-first author, †: co-corresponding author) Life 15(4): 603 (2024 Journal Impact factor: 3.2) [PubMed][pdf]

11. Kuk MU*, Lee YH*, Kim D*, Lee KS, Park JH, Yoon JH, Lee YJ, So B, Kim MS, Kwon HW, Lee KY†, Byun Y†, Park JT† (Feb 18, 2025) Sauchinone rejuvenates senescence through reducing mitochondrial ROS production. (*: co-first author, †: co-corresponding author) Antioxidants 14(3): 259 (2024 Journal Impact factor: 6) [PubMed][pdf]

12. Lee YH, Jeong EY, Kim YH, Park JH, Yoon GH, Lee YJ, Lee SH, Nam YK, Cha SY, Park JS, Kim SY, Byun Y†, Shin SS†, Park JT† (Jan 17, 2025) Identification of senescence rejuvenation mechanism of Magnolia officinalis extract including honokiol as a core ingredient. (†: co-corresponding author) Aging 17(2): 497–523 (2024 Journal Impact factor: 5) [PubMed][pdf]

[2024]

1. Kuk MU*, Kim D*, Lee YH, Yoon JH, Park JH, Lee YJ, So B, Kim MS, Kwon HW, Byun Y†, Park JT† (Nov 28, 2024) Synergistic ROS Reduction Through the Co-Inhibition of BRAF and p38 MAPK Ameliorates Senescence. (*: co-first author, †: co-corresponding author) Antioxidants 13(12): 1465 (2024 Journal Impact factor: 6) [PubMed][pdf]

2. Kuk MU, So MK, Park JH, Yoon JH, Lee YJ, Kim D, So B, Lee YH, Kim M, Byun Y, Kwon HW†, Park JT† (Oct 03, 2024) ROSA26 BAC-based System Enables Continuous High-yield Protein Production. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 29:1025–1033 (2024 Journal Impact factor: 2.5) [PubMed][pdf]

3. Yoon JH*, Kim YH*, Jeong EY‡, Lee YH‡, Byun Y, Shin SS†, Park JT† (Sep 10, 2024) Senescence rejuvenation through reduction of mitochondrial ROS generation by Polygonum cuspidatum extract: in vitro evidence (*: co-first author, ‡: co-second author, †: co-corresponding author) Antioxidants 13(9): 1110 (2024 Journal Impact factor: 6) [PubMed][pdf]

4. Lee YH*, Kuk MU*, Park JH*, Lee H, Lee H, So MK, Yoon JH, Lee YJ, Kim D, So B, Kim MS, Park J, Han T†, Park JT† (Sep 05, 2024) Rapid and accurate ecotoxicological assessment of heavy metals using Cyprinus carpio cells (*: co-first author, †: co-corresponding author) Life 14(9): 1119 (2024 Journal Impact factor: 3.2)[PubMed][pdf]

5. Lee YH, So BH, Lee KS, Kuk MU, Park JH, Yoon JH, Lee YJ, Kim DY, Kim MS, Kwon HW, Byun Y†, Lee KY†, Park JT† (Sep 05, 2024) Identification of cellular isoschaftoside-mediated anti-senescence mechanism in RAC2 and LINC00294 (†: co-corresponding author) Molecules 29(17): 4182 (2024 Journal Impact factor: 4.2)[PubMed][pdf]

6. Song ES, Lee YH, So MK, Kuk MU, Park J, Yoon JH, Lee YJ, Kim D, So B, Byun Y, Kwon HW†, Park JT† (Mar 05, 2024) Establishment of a new promoter trapping vector using 2A peptide. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 29(3):520–528 (2024 Journal Impact factor: 2.5)[PubMed][pdf]

7. Lim JS, Jeon EJ, Go HS, Kim H, Kim KY, Nguyen T, Lee DY, Kim KS, Pietrocola F, Hong SH, Lee SE, Kim K, Park TS, Choi D, Jeong Y, Park Jong, Kim HS, Min J, Kim YS, Park JT, Cho J, Lee G, Lee JH, Choy HE, Park SC, Lee C, Rhee JH, Serrano M, Cho KA (Jan 02, 2024) Mucosal TLR5 activation controls healthspan and longevity. Nature Communications 15(1):46 (2024 Journal Impact factor: 16.6) [PubMed][pdf]

8. Lee YH, Kuk MU, So MK, Park HJ, Song ES, Park J, Yoon JH, Kwon HW†, Choi J†, Park JT† (Nov 14, 2023) Polyporus ulleungus mycelia cultured in MEB medium produce metabolites with anticancer property. (†: co-corresponding author) Journal of Cancer 15(2):309-316 (2022 Journal Impact factor: 4.478) [PubMed][pdf]

[2023]

1. Song ES, So MK, Park HJ, Lee H, Lee YH, Kuk MU, Park J, Kwon HW, Choi J†, Park JT† (Jul 09, 2023) Chemical screening identifies the anticancer properties of Polyporous tuberaster. (†: co-corresponding author) Journal of Cancer 14(11): 2075-2084 (2022 Journal Impact factor: 4.478) [PubMed][pdf]

2. Lee YH*, Kuk MU*, So MK, Song ES, Lee H, Ahn S, Kwon HW†, Park JT†, Park SC† (Apr 15, 2023) Targeting Mitochondrial Oxidative Stress as a Strategy to Treat Aging and Age-Related Diseases. (*: co-first author, †: co-corresponding author) Antioxidants 12:934 (2022 Journal Impact factor: 7.675) [PubMed][pdf]

3. Lee H, Song ES, Lee YH, Park JY, Kuk MU, Kwon HW, Roh H†, Park JT† (Feb 07, 2023) A novel hybrid promoter capable of continuously producing proteins in high yield. (†: co-corresponding author) Biochemical and Biophysical Research Communications 650: 103-108 (2022 Journal Impact factor: 3.322) [PubMed][pdf]

4. Kuk MU, Lee H, Song ES, Lee YH, Park JY, Jeong S, Kwon HW, Byun Y†, Park SC†, Park JT† (Jan 16, 2023) Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence. (†: co-corresponding author) Experimental Gerontology 173:112091 (2022 Journal Impact factor: 4.253) [PubMed][pdf]

5. Lee YH, Kim M, Park HJ, Park JY, Song ES, Lee H, Ko G, Ahn S, Kwon HW, Byun Y, Kim C†, Choi J†, Park JT† (Jan 01, 2023) Chemical screening identifies the anticancer properties of Polyporous parvovarius. (†: co-corresponding author) Journal of Cancer 14(1):50-60 (2022 Journal Impact factor: 4.478) [PubMed][pdf]

[2022]

1. Park JY, Lee H, Song ES, Lee YH, Kuk MU, Ko G, Byun YJ†, Kwon HW†, Park JT† Improvement of Tol2 transposon system by modification of Tol2 transposase. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 27(6): 987-994 (2022 Journal Impact factor: 2.836) [PubMed][pdf]

2. Choi S, Lee H, Lee M, Park JT, Heynderickx PM, Wu D, Depuydt S, Asselman J, Janssen C, Häder DP, Han T, Park J (Nov 05, 2022) A Ten-Minute Bioassay to Test Metal Toxicity with the Freshwater Flagellate Euglena agilis. Biology 11(11):1618 (2022 Journal Impact factor: 5.168) [PubMed][pdf]

3. Kuk MU, Ga YJ, Kim YJ, Park JY, Song ES, Lee H, Lee YH, Ko G, Kim JK, Yeh JY, Kwon HW†, Byun YJ†, Park JT† (Oct 24, 2022) Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3. (†: co-corresponding author) Animal Cells and Systems 26(6) 275–28 (2022 Journal Impact factor: 1.815)[PubMed][pdf]

4. Park JY, Lee H, Song ES, Lee YH, Kuk MU, Ko G, Kwon HW†, Byun YJ†, Park JT† (Oct 07, 2022) Restoration of lysosomal and mitochondrial function through p38 MAPK inhibition ameliorates senescence. (†: co-corresponding author) Rejuvenation Research 25(6):291-299 (2022 Journal Impact factor: 4.663) [PubMed][pdf]

5. Yang EJ, Park JH, Cho HJ, Hwang J, Woo S, Park CH, Kim SY, Park JT, Park SC, Hwang D, Lee Y (Jul 14, 2022) Co-inhibition of ATM and ROCK synergistically improves cell proliferation in replicative senescence by activating FOXM1 and E2F1. Commun Biol. 2022 5(1):702 (2024 Journal Impact factor: 5.2) [PubMed][pdf]

6. Lee YH, Park JY, Song ES, Lee H, Kuk MU, Joo JH, Roh H†, Park JT† (Jun 25, 2022) Improvement of Sleeping Beauty transposon system enabling efficient and stable protein production. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 27(3): 353-360 (2022 Journal Impact factor: 2.836) [PubMed][pdf]

7. Kuk MU, Park JY, Song ES, Lee H, Lee YH, Joo JH, Kwon HW†, Park JT† (May 24, 2022) Bacterial artificial chromosome-based protein expression platform using the Tol2 transposon system. (†: co-corresponding author) Biotechnology and Bioprocess Engineering 27(3): 344-352 (2022 Journal Impact factor: 2.836) [PubMed][pdf]

8. Park JT, Oh S (Mar 03, 2022) The translational landscape as regulated by the RNA helicase DDX3. BMB Rep. 55(3): 125-135 (2021 Journal Impact factor: 4.16) [PubMed][pdf]

9. Lee YH, Choi D, Jang G, Park JY, Song ES, Lee H, Kuk MU, Joo JH, Ahn SK, Byun Y†, Park JT† (Jan 30, 2022) Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence. (†: co-corresponding author) Aging 14(2):678-707 (2020 Journal Impact factor: 5.682) [PubMed][pdf]

[2021]

1. Kuk MU, Lee YH, Kim JW, Hwang SY, Park JY, Song ES, Kwon HW, Oh S, Park JT (Dec 31, 2021) Rapid and Efficient BAC Recombineering: Gain & Loss Screening System. Biotechnology and Bioprocess Engineering 26(6): 1023-1033 (2020 Journal Impact factor: 2.213) [PubMed][pdf]

2. Lee YH, Park JY, Lee H, Song ES, Kuk MU, Joo JH, Oh S, Kwon HW†, Park JT†, Park SC† (Nov 03, 2021) Targeting mitochondrial metabolism as a strategy to treat senescence (†: co-corresponding author) Cells 10(11): 3003 (2021 Journal Impact factor: 6.600) [PubMed][pdf]

3. Kim JW, Lee YH, Kuk MU, Hwang SY, Kwon HW, Park JT (Oct 31, 2021) Cre/Lox-based RMCE for site-specific integration in CHO cells. Biotechnology and Bioprocess Engineering 26(5): 795-803 (2020 Journal Impact factor: 2.213) [PubMed][pdf]

4. Hwang SY, Lee YH, Kuk MU, Kim JW, Oh S, Park JT (Oct 31, 2021) Improvement of Tol2 transposon system enabling efficient protein production in CHO cells. Biotechnology and Bioprocess Engineering 26(5): 767-775 (2020 Journal Impact factor: 2.213) [PubMed][pdf]

5. Lee HJ, Stephen Depuydt, Shin KS, Choi SY, Kim GH, Lee YH, Park JT, Han TJ, Park JH (Jul 02, 2021), Assessment of various toxicity endpoints in duckweed (Lemna minor) at the physiological, biochemical, and molecular levels as a measure of diuron stress. Biology. 10(7):684 (2024 Journal Impact factor: 3.6) [PubMed][pdf]

6. Park JH, Ryu SJ, Kim BJ, Cho HJ, Park CH, Choi HJC, Jang EJ, Yang EJ, Hwang JA, Woo SH, Lee JH, Park JH, Choi KM, Kwon YY, Lee CK, Park JT, Cho SC, Lee YI, Lee SB, Han JA, Cho KA, Kim MS, Hwang D, Lee YS, Park SC (Jun 29, 2021) Disruption of nucleocytoplasmic trafficking as a cellular senescence driver. Exp Mol Med 53:1092-1108 (2024 Journal Impact factor: 9.5) [PubMed][pdf]

7. Kuk MU, Lee YH, Kim JW, Hwang SY, Park JT†, Park SC† (Feb 17, 2021) Potential Treatment of Lysosomal Storage Disease Through Modulation of the Mitochondrial–Lysosomal Axis. (†: co-corresponding author) Cells. 10(2): 420. (2020 Journal Impact factor: 4.829) [PubMed][pdf]

8. Klionsky DJ, …, Park JT…, Tong C (Feb 08, 2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 17(1):1–382 (2026 Journal Impact factor: 18.6) [PubMed][pdf]

9. Song N, Jeong DY, Tu TH, Park BS, Yang HR, Kim YJ, Kim JK, Park JT, Yeh JY, Yang S, Kim JG (Feb 04, 2021) Adiponectin Controls Nutrient Availability in Hypothalamic Astrocytes. Int J Mol Sci. 22(4):1587 (2024 Journal Impact factor: 4.9) [PubMed][pdf]

10. Park JH, Lee HJ, Choi SY, Pandey LK, Depuydt S, Saeger JD, Park JT, Han TJ (Jan 04, 2021) Extracts of red seaweed, Pyropia yezoensis, inhibit melanogenesis but stimulate collagen synthesis. Journal of Applied Phycology. 33:653–662 (2024 Journal Impact factor: 2.8) [PubMed][pdf]

[2020]

1. Hwang SY, Kuk MU, Kim JW, Lee YH, Lee YS, Choy HE, Park SC, Park JT (Nov 01, 2020) ATM mediated-p53 signaling pathway forms a novel axis for senescence control. Mitochondrion 55:54-63 (2020 Journal Impact factor: 3.430) [PubMed][pdf]

2. Lim JS, Lee DY, Kim HS, Park SC, Park JT, Kim HS, Oh WK, Cho KA (Dec 01, 2020) Identification of a novel senomorphic agent, avenanthramide C, via the suppression of the senescence-associated secretory phenotype. Mech Ageing Dev. 192:111355 (2024 Journal Impact factor: 5.3) [PubMed][pdf]

3. Cho HJ, Yang EJ, Park JT, Kim JR, Kim EC, Jung KJ, Park SC, Lee YS (May 07, 2020) Identification of SYK inhibitor, R406 as a novel senolytic agent. Aging 12(9):8221-8240 (2019 Journal Impact factor: 4.831)[PubMed][pdf]

[2019]

1. Kim JW*, Kuk MU*, Choi HE, Park SC†, Park JT† (Oct 15, 2019) Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. (*: co-first author, †: co-corresponding author) Exp Gerontol. 126: 110691 (2019 Journal Impact factor: 3.08) [PubMed][pdf]

2. Oh S, Park JT (May 10, 2019) Zebrafish model of KRAS-initiated pancreatic endocrine tumor. Animal Cells and Systems. 23(3):209-218 (2019 Journal Impact factor: 0.549) [PubMed][pdf]

3. Kuk MU*, Kim JW*, Lee YS, Cho KA, Park JT†, Park SC† (Mar 31, 2019) Alleviation of senescence via ATM inhibition in accelerated aging models. (*: co-first author, †: co-corresponding author) Mol Cells. 42(3):210-217 (2019 Journal Impact factor: 3.533) [PubMed][pdf]

4. Kang SU, Park JT (Feb 01, 2019) Functional evaluation of alternative splicing in the FAM190A gene. Genes & Genomics. 41(2):193-199 (2019 Journal Impact factor: 1.188) [PubMed][pdf]

[2018]

1. Park JT, Lee YS, Park SC (Nov 25, 2018) Quantification of Autophagy During Senescence. Methods Mol Biol. 1896:149-157 (2019 Journal Impact factor: 0.91) [PubMed][pdf]

2. Park JT, Leach SD (Oct 08, 2018) Zebrafish model of KRAS-initiated pancreatic cancer. Animal Cells and Systems. 22(6): 353-359 (2019 Journal Impact factor: 0.549) [PubMed][pdf]

3. Park JT, Lee YS, Cho KA, Park SC (Nov 01, 2018) Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence. Ageing Res Rev. 47:176-182 (2019 Journal Impact factor: 10.39) [PubMed][pdf]

4. Park JT, Kang HT, Park CH, Lee YS, Cho KA, Park SC (Jun 01, 2018) A crucial role of ROCK for alleviation of senescence-associated phenotype. Exp Gerontol. 106:8-15 (2019 Journal Impact factor: 3.08) [PubMed][pdf]

[2017]

1. Kang HT*, Park JT*†, Choi K*, Choi HJ, Jung CW, Lee YS†, ParkSC† (Mar 27, 2017). Chemical screening identifies ATM as a target for alleviating senescence (As co-first and co-corresponding author) Nat Chem Biol. 13:616-623. (2019 Journal Impact factor: 12.154) [PubMed][pdf]

2. Kang HT*, Park JT*†, Choi K, Choi HJ, Jung CW, Kim GR, Lee YS†, ParkSC† (Jun 01, 2017). Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome (As co-first and co-corresponding author) Aging Cell 16(3):541-550. (2019 Journal Impact factor: 7.346) [PubMed][pdf]

[2016]
1. Jung JG, Shih IM, Park JT, Gerry E, Kim TH, Ayhan A, Handschuh K, Davidson B, Nickles Fader A, Selleri L, Wang TL (Nov 01, 2016). Ovarian cancer chemoresistance relies on the stem cell reprogramming factor PBX1. Cancer Res. 76(21):6351-6361 (2024 Journal Impact factor: 12.5) [PubMed][pdf]

[2015]
1. Park JT, Johnson N, Liu S, Levesque M, Wang YJ, Ho H, Huso D, Maitra A, Parsons MJ, Prescott JD, Leach SD (May 21, 2015). Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey. Oncogene 34(21): 2801–2806. (2019 Journal Impact factor: 6.634) [PubMed][pdf]

2. Kim MS, Jo S, Park JT, Shin HY, Kim SS, Gurel O, Park SC (Aug 31, 2015). Method To Purify and Analyze Heterogeneous Senescent Cell Populations Using a Microfluidic Filter with Uniform Fluidic Profile. Anal Chem. 87(19):9584-8 (2024 Journal Impact factor: 6.7) [PubMed][pdf]

3. Wang YJ, Park JT, Parsons MJ, Leach SD (Jun 01, 2015). Fate mapping of ptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish. Dev Dyn. 244:724-35 (2024 Journal Impact factor: 2.0) [PubMed][pdf]

[2013]
1. Park JT, Leach SD. (Dec 31, 2013) TAILOR (Transgene Activation and Inactivation with LOx and Rox). PLOS ONE 8: e85218 (2019 Journal Impact factor: 2.776) [PubMed][pdf]

2. Pashos E, Park JT, Leach S, Fisher S (Sep 15, 2013). Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish. Dev Biol. 381:471-481 (2024 Journal Impact factor: 2.0)[PubMed][pdf]

3. Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng CX, Ye Z, Jang YY (Jun 01, 2013). Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology 57(6): 2458–2468 (2024 Journal Impact factor: 26.8) [PubMed][pdf]

[2010]
1. Park JT, Chen X, Trope CG,Davidson B, Shih IeM, Wang TL (Sep 01, 2010). Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin. Am J Pathol. 177(3):1087-94 (2019 Journal Impact factor: 3.762) [PubMed][pdf]

[2008]

1. Park JT, Shih IeM, Wang TL (Nov 01, 2008). Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. Cancer Res 68(21): 8852-8860 (2019 Journal Impact factor: 8.378) [PubMed][pdf]

2. Choi JH, Park JT, Davidson B, Morin PJ, Shih IeM, Wang TL (Jul 15, 2008). Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Res. 68(14):5716-23 (2024 Journal Impact factor: 12.5) [PubMed][pdf]

[2007]

1. Park JT, Ahn TI (Jun 01, 2006). A Novel Ubiquitin-Like Protein Gene Expression During the Cyst Maturation in Acanthamoeba castellanii. Korean Journal of Genetics 29(2): 219-227. (2003 Journal Impact factor: 0.562) [PubMed][pdf]

[2006]

1. Park JT, Li M, Nakayama K, Mao TL, Davidson B, Zhang Z, Kurman RJ, Eberhart CG, Shih IeM, Wang TL (Jun 15, 2006). Notch3 gene amplification in ovarian cancer. Cancer Res. 66(12):6312-8 (2019 Journal Impact factor: 8.378) [PubMed][pdf]

[2005]
1. Choi KS, Park JT, Dumler JS (Dec 01, 2005) Anaplasma phagocytophilum delay of neutrophil apoptosis through the p38 mitogen-activated protein kinase signal pathway. Infect Immun. 73(12):8209-18 (2024 Journal Impact factor: 2.9) [PubMed][pdf]

[2002]

1. Park JT, Jung YE, Ahn TI (Dec 01, 2002) Changes in profiles of major proteins in encysting Acanthamoeba castellanii Korean J. Biol. Sci. 6: 341-347 (2024 Journal Impact factor: 4.21) [PubMed][pdf]

Book Chapters

[2009]
1. Park JT, Shih IeM, Wang TL (2009) Targeting Notch Signaling Pathway in Cancer Stem Cell. Cancer Stem Cells Cambridge University Press; 128-138 [pdf]

Book Translation

[2025]

1.캠벨 생명과학 포커스, 4판 (Jan 31, 2025). ㈜바이오사이언스 출판 [LINK]

[2022]

1. 캠벨 생명과학, 12판 (Mar 10, 2022). ㈜바이오사이언스 출판 [LINK]

2. 캠벨 생명과학의 이해, 2nd edition (Mar 10, 2022). ㈜바이오사이언스 출판 [LINK]

[2021]

1.캠벨 생명과학 포커스, 3판 (Mar 10, 2021). ㈜바이오사이언스 출판 [LINK]

[2019]
1. 캠벨 생명과학, 11판 (Mar 30, 2019). ㈜바이오사이언스 출판 [LINK]

문의

Patent

Korean Patent (Filling)

[2026]

1. 김민선, 박지호, 이호준, 박지혜, 한태준, 박준태 (Aug 21, 2026), 누치 세포를 이용한 평가 대상 물질의 독성 평가방법, 10-2026-0158048 (Filling) [pdf]

2. 김민선, 김두열, 권형욱, 변영주, 이기용, 박준태 (Apr 08, 2026), 메틸니솔린 3-O-β-글루코사이드를 유효성분으로 포함하는 항노화 조성물, 10-2026-0063626 (Filling) [pdf]

3. 김민선, 권형욱, 변영주, 이기용, 박준태 (Jan 20, 2026), LOC107987118 유전자 발현 억제제를 유효성분으로 포함하는 항노화 조성물, 10-2026-0011021 (Filling) [pdf]

[2025]

1. 윤지희, 김두열, 김예향, 정은영, 변영주, 신송석, 박준태 (Nov 24, 2025), 레스베라트롤 유도체를 함유하는 세포 회복용 또는 피부 활력 개선용 화장료 조성물, 10-2025-0179205 (Filling) [pdf]

2. 김두열, 권형욱, 변영주, 이기용, 박준태 (Nov 12, 2025), 바니코시드 B를 유효성분으로 포함하는 항노화 조성물, 10-2025-0170558 (Filling) [pdf]

3.박지호, 차소윤, 김하연, 남연경, 정은영, 김소연, 박진성, 이윤행, 권형욱, 변영주, 신송석, 박준태 (Jul 31, 2025), 세노몰픽 및 세놀리틱 효능을 갖는 하동작설 유래 역노화 조성물, 10-2025-0105474 (Filling) [pdf]

4. 김민선, 박지호, 소병현, 이윤행, 이호준, 박지혜, 한태준, 박준태 (Jul 25, 2025), 버들붕어 세포를 이용한 독성물질의 유전독성 평가방법, 10-2025-0101173 (Filling) [pdf]

5. 소병현, 박지호, 김민선, 이윤행, 이호준, 박지혜, 한태준, 박준태 (Jul 25, 2025), 민물고기 세포를 이용한 독성물질의 유전독성 평가방법, 10-2025-0101172 (Filling) [pdf]

6. 국명욱, 김두열, 이윤행, 변영주, 박준태 (Feb 27, 2025), BRAF 억제제 및 p38 MAPK 억제제를 유효성분으로 포함하는 항노화 조성물, 10-2025-0025992 (Filling) [pdf]

7. 윤지희, 국명욱, 권형욱, 변영주, 김예향, 차소윤, 김하연, 남연경, 정은영, 김소연, 박진성, 신송석, 박준태 (Jan 31, 2025), 세포 노화 및 대사 기능 회복 효능을 갖는 호장근 유래 역노화 조성물, 10-2025-0012464 (Filling) [pdf]

[2024]

1. 이윤행, 권형욱, 변영주, 임현웅, 박준태 (Dec 18, 2024), 옥사졸 유도체를 유효성분으로 포함하는 항노화 조성물, 10-2024-0190507 (Filling) [pdf]

2. 소문경, 이윤행, 권형욱, 박준태 (Aug 16, 2024), 펩톤 및 FBS를 포함하는 CHO 세포 배양용 DMEM 배지 조성물, 10-2024-0109929 (Filling) [pdf]

3. 이윤행, 권형욱, 변영주, 임현웅, 박준태 (Aug 16, 2024), 피라졸 유도체를 유효성분으로 포함하는 항노화 조성물, 10-2024-0109860 (Filling) [pdf]

4. 이윤행, 이유진, 권형욱, 변영주, 김예향, 이소헌, 차소윤, 남연경, 정은영, 김소연, 박진성, 신송석, 박준태 (Jul 30, 2024), 세포 노화 및 대사 기능 회복 효능을 갖는 후박나무 유래 역노화 조성물, 10-2024-0100729 (Filling) [pdf]

5. 이유진, 송은선, 권형욱, 임현웅, 변영주, 박준태 (Jun 13, 2024), 피라졸 유도체를 유효성분으로 포함하는 항노화 조성물, 10-2024-0077014 (Filling) [pdf]

6. 이유진, 송은선, 권형욱, 변영주, 이기용, 박준태 (May 03, 2024), 디히드로악테오사이드를 유효성분으로 포함하는 항노화 조성물, 10-2024-0059125 (Filling) [pdf]

7. 윤지희, 권형욱, 변영주, 이기용, 박준태 (May 02, 2024), 비티신 B를 유효성분으로 포함하는 항노화 조성물, 10-2024-0058770 (Filling) [pdf]

8. 국명욱, 김두열, 권형욱, 변영주, 이기용, 박준태 (Apr 30, 2024), 사우치논을 유효성분으로 포함하는 항노화 조성물, 10-2024-0058049 (Filling) [pdf]

9. 박지호, 권형욱, 변영주, 이기용, 박준태 (Apr 30, 2024), ε-비니페린을 유효성분으로 포함하는 항노화 조성물, 10-2024-0057851 (Filling) [pdf]

10. 이윤행, 소병현,권형욱, 변영주, 이기용, 박준태 (Apr 29, 2024), 이소샤프토사이드를 유효성분으로 포함하는 항노화 조성물, 10-2024-0056806 (Filling) [pdf]

11. 국명욱, 권형욱, 변영주, 박준태 (Feb 16, 2024), 결손된 iMAR 유전자를 포함하는 목적 단백질 발현 카세트 및 벡터 및 이를 포함하는 형질전환 세포, 10-2024-0022827 (Filling) [pdf]

[2023]

1. 이윤행, 권형욱, 변영주, 박준태 (Aug 29, 2023), 옥사졸 유사체를 유효성분으로 포함하는 항노화 조성물, 10-2023-0113722 (Filling) [pdf]

2. 이하늘, 변영주, 박준태 (Aug 22, 2023), 신규한 프로모터, 10-2023-0110153 (Filling) [pdf]

[2022]

1. 국명욱, 이윤행, 권형욱, 변영주, 박준태 (Jul 29, 2022), AKT 저해제를 포함하는 미토파지 활성화 방법, 10-2022-0095033 (Filling) [pdf]

[2021]

1. 이윤행, 변영주, 최도영, 박준태 (Feb 18, 2021), 세포노화 관련 질병의 예방 또는 치료용 약학적 조성물, 10-2021-0022067 (Filling) [pdf]

Korean Patent (Registration)

[2026]

1. 국명욱, 권형욱, 박준태 (Jul 06, 2026), ROSA26 박테리아 인공염색체 내인성 프로모터, 10-2988970 (Registration) [pdf]

2. 이하늘, 이윤행, 박지호, 국명욱, 김두열, 소병현, 한태준, 이호준, 박지혜, 박준태 (Jun 19, 20246), 민물고기 세포의 생존능 특성을 이용한 생태독성 평가방법, 10-2981516 (Registration) [pdf]

3. 이윤행, 권형욱, 변영주, 박준태 (Aug 16, 2026), 옥사졸 유사체를 유효성분으로 포함하는 항노화 조성물, 10-2955312 (Registration) [pdf]

4. 송은선, 권형욱, 변영주, 박준태 (Mar 04, 2026), RMCE 랜딩패드, 10-2936696 (Registration) [pdf]

[2025]

1. 송은선, 최재혁, 임영운, 박준태 (Dec 30, 2025), 항암 활성을 가지는 폴리포루스 튜버래스터 균주 배양방법, 10-2907970 (Registration) [pdf]

2. 이윤행, 최재혁, 김창무, 김민경, 안초롱, 유영현, 지원재, 임영운, 박준태 (Dec 29, 2025), 항암 활성을 가지는 폴리포루스 울릉구스 균주, 10-2907192 (Registration) [pdf]

3. 국명욱, 박지윤, 권형욱, 변영주, 박준태 (Dec 03, 2025), 콕사키바이러스 B3 감염 치료 또는 예방용 조성물, 10-2897391 (Registration) [pdf]

4. 박준태, 이경주, 임주송, 임형택, 허윤정, 이재선, 민호성 (Nov 26, 2025) 세포 배양 배지에서 원치 않는 배양 부산물을 감소시키는 공정, 10-2893388 (Registration) [pdf]

5. 이윤행, 박지윤, 한태준, 박지혜, 이호준, 박준태 (Sep 24, 2025) 민물고기 세포의 증식 특성을 이용한 생태독성 평가방법, 10-2865566 (Registration) [pdf]

6. 박지윤, 박준태 (Jun 20, 2025), 신규한 트랜스포사제 및 이를 이용한 트랜스포존 시스템, 10-2825196 (Registration) [pdf]

[2024]

1. 이하늘, 권형욱, 변영주, 박준태 (Dec 27, 2024), 하이브리드 프로모터, 10-2749407 (Registration) [pdf]

2. 이윤행, 최재혁, 김창무, 김민경, 안초롱, 유영현, 지원재, 박준태 (Oct 16, 2024), 항암 활성을 가지는 폴리포루스 파보바리우스(Polyporus parvovarius) 균주, 10-2021-0156407 (Registration) [pdf]

[2022]

1. 국명욱, 박준태 (Apr 04, 2022), 박테리아 인공 염색체 재조합 스크리닝 방법, 10-2384173 (Registration) [pdf]

2. 이윤행, 박준태 (Feb 16, 2022), 개선된 슬리핑 뷰티 트랜스포존 시스템 및 이를 이용한 유전자 전위 방법, 10-2365768 (Registration) [pdf]

3. 황수영, 박준태 (Feb 09, 2022), CHO 세포에 전이 유전자를 통합하기 위한 방법, 10-2362878 (Registration) [pdf]

4. 최고봉, 박준태, 강현태 (Feb 03, 2022) Smurf2의 저해제를 포함하는 세포 또는 개체의 노화를 감소시키기 위한 조성물 및 그의 용도, 10-2360028 (Registration) [pdf]

5. 국명욱, 박준태 (Jan 10, 2022), Tol2 트랜스포존 시스템을 포함하는 인공 염색체 및 이를 이용한 단백질 생산 방법, 10-2350981 (Registration) [pdf]

[2021]

1. 김재원, 박준태 (Nov 30, 2021), Fer1L4 유전자에 부위-특이적 통합된 RMCE 랜딩 패드를 포함하는 CHO 세포, 10-2335242 (Registration) [pdf]

2. 박준태, 강현태, 정철원, 최고봉, 박상철, 최효제 (Jul 06, 2021), 로-키나제 저해제를 포함하는 세포의 노화를 감소시키기 위한 조성물 및 그의 용도, 10-2276424 (Registration) [pdf]

International Patent (Filling)

[2026]

1. 김민선, 김두열, 권형욱, 변영주, 이기용, 박준태 (Sep 08, 2026), 메틸니솔린 3-O-β-글루코사이드를 유효성분으로 포함하는 항노화 조성물, PCT/KR2026/013520 (Filling) [pdf]

2. 윤지희, 김두열, 김예향, 정은영, 변영주, 신송석, 박준태 (Aug 28, 2026), 레스베라트롤 유도체를 함유하는 세포 회복용 또는 피부 활력 개선용 화장료 조성물, PCT/KR2026-012677 (Filling) [pdf]

3. 이윤행, 권형욱, 임현웅, 변영주, 박준태 (Mar 02, 2026), ANTI-AGING COMPOSITION COMPRISING OXAZOLE DERIVATIVE, 19/554,599 (Filling) [pdf]

[2025]

1. 윤지희, 국명욱, 권형욱, 변영주, 김예향, 차소윤, 김하연, 남연경, 정은영, 김소연, 박진성, 신송석, 박준태 (Feb 19, 2025), 세포 노화 및 대사 기능 회복 효능을 갖는 호장근 유래 역노화 조성물, PCT/KR2025/099451 (Filling) [pdf]

2. 이윤행, 권형욱, 임현웅, 변영주, 박준태 (Jan 10, 2025), 옥사졸 유도체를 유효성분으로 포함하는 항노화 조성물, PCT/KR2025/000594 (Filling) [pdf]

[2024]

1. 이윤행, 이유진, 권형욱, 변영주, 김예향, 이소헌, 차소윤, 남연경, 정은영, 김소연, 박진성, 신송석, 박준태 (Oct 18, 2024), 세포 노화 및 대사 기능 회복 효능을 갖는 후박나무 유래 역노화 조성물, PCT/KR2024/015910 (Filling) [pdf]

2. 이윤행, 변영주, 권형욱, 박준태 (Aug 28, 2024), 옥사졸 유사체를 유효성분으로 포함하는 항노화 조성물, PCT/KR2024/012827 (Filling) [pdf]

[2021]

1. Lee YH, Byun YJ, Choi DY, Park JT (Jul 23, 2021), PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING AGING OR AGE-RELATED DISEASES, PCT/KR2021/009592 (Filling) [pdf]

2. Kuk MU, Park JT (Feb 19, 2021), ARTIFICIAL CHROMOSOME COMPRISING TOL2 TRANSPOSON SYSTEM AND PROTEIN PRODUCTION METHOD USING SAME, PCT/KR2021/002138 (Filling) [pdf]

[2020]

1. Lee YH, Park JT (Dec 07, 2020), DEVELOPED SLEEPING BEAUTY TRANSPOSON SYSTEM AND METHOD OF GENE TRANSPOSITION USING THEREOF, PCT/KR2020/017709 (Filling) [pdf]

2. Kuk MU, Park JT(Aug 27, 2020), SCREENING METHOD OF BACTERIAL ARTIFICIAL CHROMOSOMES RECOMBINEERING, PCT/KR2020/011464 (Filling) [pdf]

International Patent (Registration)

[2025]

1. Lee YH, Byun YJ, Choi DY, Park JT (Sep 30, 2025), PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING AGING OR AGE-RELATED DISEASES, US12427143B2 (Registration) [pdf]

[2020]

1. Park JT, Lee KJ, Lim JS, Lim HT, Heo YJ, Lee JS, Min HS (Nov 05, 2020), Process for reducing undesirable by-product in cell culture, AU2017349343B2 (Registration) [pdf]

[2018]
1. Choi K*, Park JT, Kang HT (Apr 24, 2018), Composition for reducing senescence of cell or subject comprising smurf2 inhibitor and use thereof, US9951336B2 (Registration) [pdf]

2. Park JT, Kang HT, Jung CW, Choi K, Park SC, Choi HJ (Apr 17, 2018), COMPOSITION FOR REDUCING CELL SENESCENCE COMPRISING RHO-KINASE INHIBITOR AND USE THEREOF, US9943525B2 (Registration) [pdf]

[2017]

1. Jung CW*, Park JT*, Kang HT, Park SC, Choi HJ, Choi K (Sep 26, 2017), COMPOSITION INCLUDING ATM INHIBITOR FOR REDUCING CELLULAR SENESCENCE AND USE OF THE COMPOSITION, US9770451B2 (Registration) [pdf]

2. Keum JW*, Park JT*, Jung CW, Park SC, Lee YS (Sep 19, 2017), COMPOSITION FOR REDUCING SENESCENCE OF CELL OR SUBJECT INCLUDING BRAF INHIBITOR AND USE THEREOF, US9763923B2 (Registration) [pdf]

앵커 1

앵커 2

Courses

[2022]

Protein Engineering

Main Teaching Material
Proteins: Structure and Function
by David Whitford

Chapter 1. An introduction to protein structure and function [link]
Chapter 2. Amino acids: the building blocks of proteins [link]
Chapter 3. The three-dimensional structure of proteins [link]

Chapter 1 & 2 & 3 summary by ZOOM [link]
Chapter 4. The structure and function of fibrous proteins [link]
Chapter 5. The structure and function of membrane proteins [link]

Chapter 4 & 5 summary by ZOOM [link]
Chapter 6. The diversity of proteins [link]
Chapter 7. Enzyme kinetics, structure, function and catalysis [link]

Chapter 6 & 7 summary by ZOOM [link]
Chapter 8. Protein synthesis, processing and turnover [link]
Chapter 9. Protein expression, purification and characterization [link]
Chapter 11. Protein folding in vivo and in vitro [link]

Chapter 8 & 9 & 11 summary by ZOOM [link]

[2022]

Genetics

Main Teaching Material
Genetics: A Conceptual Approach, 6th Edition
by Benjamin A. Pierce

Chapter 1. Introduction to Genetics [link]

Chapter 2. Chromosomes and Cellular Reproduction [link]

Chapter 3. Basic Principles of Heredity [link]

Chapter 4. Sex Determination and Sex-Linked Characteristics [link]

Chapter 1 & 2 & 3 & 4 summary by ZOOM [link]

Chapter 5. Extensions and Modifications of Basic Principles [link]

Chapter 6. Pedigree Analysis, Applications, and Genetic Testing [link]

Chapter 5 & 6 summary by ZOOM [link]

Chapter 7. Linkage, Recombination, and Eukaryotic Gene Mapping [link]

Chapter 8. Chromosome Variation [link]

Chapter 7 & 8 summary by ZOOM [link]

Chapter 9. Bacterial and Viral Genetic Systems [link]

Chapter 10. DNA: The Chemical Nature of the Gene [link]

Chapter 11. Chromosome Structure and Organelle DNA [link]

Chapter 9 & 10 & 11 summary by ZOOM [link]

[2022]

Epigenetics

Main Teaching Material
Introduction to Epigenetics
by Dae Yup Lee

Chapter 1. Overview about Epigenetics [link]

Chapter 2. Epigenetics in Saccharomyces cerevisiae [link]

Chapter 1 & 2 summary by ZOOM [link]

Chapter 3. Epigenetics in Schizosaccharomyces pombe [link]

Chapter 4. Epigenetics in Fruit Fly [link]

Chapter 5. Epigenetics in Mammals [link]

Chapter 3 & 4 & 5 summary by ZOOM [link]

Chapter 6. Mono-allelic Expression [link]

Chapter 7. RNA-directed DNA Methylation(RdDM) in Plant [link]

Chapter 6 & 7 summary by ZOOM [link]

Chapter 8. Histone Variant and Epigenetics [link]

Chapter 9. Histone Ubiquitylation [link]

Chapter 10. Histone Acetylation/Deacetylation [link]

Chapter 8 & 9 & 10 summary by ZOOM [link]

[2022]

Biology foundation(1)

Main Teaching Material

Life : the science of biology 12th edition
By David M. Hillis, H. Craig Heller, Sally D. Hacker,

David W. Hall, Marta J. Laskowski, David E. Sadava

Chapter 1. Studying Life

Chapter 2. Small Molecules and the Chemistry of Life [link]

Chapter 3. Proteins, Carbohydrates, and Lipids [link]

Chapter 4. Nucleic Acids and the Origin of Life

Chapter 5. Cells: The Working Units of Life [link]

Chapter 6. Cell Membranes [link]

Chapter 7. Cell Communication and Multicellularity [link]

Chapter 8. Energy, Enzymes, and Metabolism [link]

Chapter 9. Pathways that Harvest Chemical Energy [link]

Chapter 10. Photosynthesis: Energy from Sunlight [link]

Chapter 11. The Cell Cycle and Cell Division [link]

Chapter 12. Inheritance, Genes, and Chromosomes [link]

Chapter 13. DNA and Its Role in Heredity [link]

Chapter 14. From DNA to Protein: Gene Expression [link]

Chapter 15. Gene Mutation and Molecular Medicine [link]

Chapter 16. Regulation of Gene Expression [link]

Chapter 17. Genomes [link]

Chapter 18. Recombinant DNA and Biotechnology [link]

Chapter 19. Processes of Evolution [link]

Chapter 20. Reconstructing and Using Phylogenies [link]

Chapter 21. Evolution of Genes and Genomes [link]

Chapter 22. Speciation [link]

Chapter 23. The History of Life on Earth [link]

Chapter 24. Bacteria, Archaea, and Viruses [link]

Poster Presentation

[2026]

1. Park JH, Park JT (2026) KB3407 Improves Cellular Function by Modulating LCN2-Associated Oxidative Stress in Senescent Cells, KSBMB International Conference 2026, May 27 ~ May 29, 2026, 생화학분자생물학회
2. Yoon JH, Park JT (2026) KB2779 induces senolytic activity through 14-3-3ζ and annexin V in senescent fibroblasts, KSBMB International Conference 2026, May 27 ~ May 29, 2026, 생화학분자생물학회
3. Kim M, Park JT (2026) Identification of KB4971 as an Anti-Senescence Candidate through OCR/ECAR-Based Metabolic Screening, KSBMB International Conference 2026, May 27 ~ May 29, 2026, 생화학분자생물학회
4. Song J, Park JT (2026) Methylnissolin 3-O-β-glucoside Restores Proliferation and Mitochondrial Function in Human Dermal Fibroblasts, KSBMB International Conference 2026, May 27 ~ May 29, 2026, 생화학분자생물학회
5. Choi SI, Park JT (2026) Skullcapflavone II Attenuates Cellular Senescence by Restoring Mitochondrial Function in Human Dermal Fibroblasts, KSBMB International Conference 2026, May 27 ~ May 29, 2026, 생화학분자생물학회
6. Park JH, Kim YH, Jeong EY, Shin SS, Park JT (2026) A Catechin Combination Attenuates Senescence via a Senomorphic Mechanism by Enhancing Mitochondrial OXPHOS Efficiency, 2026년도 대한화장품학회 춘계학술대회, May 15, 2026, 대한화장품학회
7. Yoon JH, Kim YH, Kim DY, Jeong EY, Shin SS, Park JT (2026) Resveratroloside attenuates cellular senescence by coordinating mitochondrial metabolism and NAD+-SIRT6-associated epigenetic remodeling, 2026년도 대한화장품학회 춘계학술대회, May 15, 2026, 대한화장품학회
8. Kim M, Yoon JH, Park JH, Jeong EY, Kim YH, Lee YH, Shin SS, Park JT (2026) Senescence Amelioration in Fibroblasts Due to Synergistic Effects of Camellia sinensis and Magnolia officinalis Extract, 2026년도 대한화장품학회 춘계학술대회, May 15, 2026, 대한화장품학회

[2025]

1. Park JT (2025) 목련 액상 추출물의 미토콘드리아 ROS 감소를 통한 피부 노화 회복, 2025년도 대한화장품학회 추계학술대회, Nov 21, 2025, 대한화장품학회

2. Park JT (2025) Rapid and Accurate Ecotoxicological Assessment Using Cyprinus carpio Cells, 2025년도 한국환경생물학회 정기학술대회, October 22th ~ October 24th 2025, 한국환경생물학회
3. Lee YH, Park JT (2025) Elucidating the mechanism of improving aging through selective death of senescent cells, 17th International Symposium on Natural Sciences, October 16th ~ October 17th, 2025, Research Institute of Basic Sciences, Incheon National University
4. Park JH, Park JT (2025) ε-Viniferin Rejuvenates Senescence via RGS16 Regulation: In Vitro Evidence, 17th International Symposium on Natural Sciences, October 16th ~ October 17th, 2025, Research Institute of Basic Sciences, Incheon National University
5. Yoon JH, Park JT (2025) Resveratroloside Exhibits Potent Anti-senescence and Longevity Effects: A Comparative and Functional Analysis Beyond Resveratrol, 17th International Symposium on Natural Sciences, October 16th ~ October 17th, 2025, Research Institute of Basic Sciences, Incheon National University
6. Lee YJ, Park JT (2025) Mitochondrial amelioration and anti-aging effects of KB3409, 17th International Symposium on Natural Sciences, October 16th ~ October 17th, 2025, Research Institute of Basic Sciences, Incheon National University
7. Kim D, Park JT (2025) Vanicoside B treatment for recovery of cellular aging through reduction of ROS, 17th International Symposium on Natural Sciences, October 16th ~ October 17th, 2025, Research Institute of Basic Sciences, Incheon National University
8. So B, Park JT (2025) Acteoside reverses cellular senescence through senolytic activity and reductions in ROS and SASP markers, 17th International Symposium on Natural Sciences, October 16th ~ October 17th, 2025, Research Institute of Basic Sciences, Incheon National University

9. Lee YH, Park JT (2025) Elucidating the mechanism of improving aging through selective death of senescent cells, 제 31차 아시아ㆍ오세아니아 생화학분자생물학회 (FAOBMB 2025), May 20 ~ May 23, 2025, 생화학분자생물학회
10. Park J, Park JT (2025) ε-Viniferin relieves oxidative stress in senescent cells through regulation of RGS16, 제 31차 아시아ㆍ오세아니아 생화학분자생물학회 (FAOBMB 2025), May 20 ~ May 23, 2025, 생화학분자생물학회
11. Yoon JH, Park JT (2025) Cellular senescence amelioration of vitisin B: regulation of WBP2NL and its role in oxidative stress reduction, 제 31차 아시아ㆍ오세아니아 생화학분자생물학회 (FAOBMB 2025), May 20 ~ May 23, 2025, 생화학분자생물학회
12. Lee YJ, Park JT (2025) Mitochondrial amelioration and anti-aging effects of KB3409, 제 31차 아시아ㆍ오세아니아 생화학분자생물학회 (FAOBMB 2025), May 20 ~ May 23, 2025, 생화학분자생물학회
13. Kim D, Park JT (2025) Vanicoside B treatment for recovery of cellular aging through reduction of ROS, 제 31차 아시아ㆍ오세아니아 생화학분자생물학회 (FAOBMB 2025), May 20 ~ May 23, 2025, 생화학분자생물학회
14. So B, Park JT (2025) A Study on the Senolytic Mechanism of Acteoside for Anti-Aging, International Conference 2025, May 20 ~ May 23, 2025, 생화학분자생물학회
15. Kim M, Park JT (2025) THE ANTIOXIDANT EFFECT OF FORMONONETIN IN ALLEVIATING SKIN AGING THROUGH MITOCHONDRIAL RESTORATION, 제 31차 아시아ㆍ오세아니아 생화학분자생물학회 (FAOBMB 2025), May 20 ~ May 23, 2025, 생화학분자생물학회

[2024]

1. Kuk MU, Park JT (2024) EXPLORING REJUVENATION EFFECTS THROUGH THE APPLICATION OF SAUCHINONE AS AN NF-ΚB INHIBITOR, 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
2. Lee YH, Park JT (2024) Identifying senolytics effect of KB2779 as an anti-senescence amelioration, 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
3. Park JH, Park JT (2024) ε-viniferin, which selectively kills cells to prevent senescence, 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
4. Yoon JH, Park JT (2024) Identification of the anti-senescence properties mechanism of vitisin B, 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
5. Lee YJ, Park JT (2024) Mitochondrial amelioration and anti-aging effects of a pyrazole analog(KB3409), 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
6. Kim DY, Park JT (2024) Synergistic effect of p38 MAPK and BRAF inhibitor at senescence amelioration(Synergy effect of SB590885 and SB203580), 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
7. So BH, Park JT (2024) Identification of cellular anti–senescence mechanism: regulatory of RAC2 and LINC00294 mediated by isoschaftoside, 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
8. Kim MS, Park JT (2024) Ecotoxicity assessment in Macropodus opercularis using EC50 and comet assay, 16th International Symposium on Natural Sciences, October 10th ~ October 11th, 2024, Research Institute of Basic Sciences, Incheon National University
9. Kuk MU, Park JT (2024) Mitochondrial dysfunction caused by the 3C protease of coxsackievirus B3 in HeLa cell, 2024 한국방역학회 춘계학술대회 May 30, 2024, 한국방역학회
10. Kuk MU, Park JT (2024) THE ROSA26 BAC ENDOGENOUS PROMOTER ENHANCE THE SYNTHESIS OF RECOMBINANT PROTEINS, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
11. Kuk MU, Park JT (2024) MINIMIZATION OF HUMAN ΒETA-INTERFERON MARS IN RECOMBINANT PROTEIN PRODUCTION SYSTEMS, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
12. Kuk MU, Park JT (2024) EXPLORING REJUVENATION EFFECTS THROUGH THE APPLICATION OF SAUCHINONE AS AN NF-ΚB INHIBITOR, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
13. Lee YH, Park JT (2024) Identifying senolytics effect of KB2779 as an anti-senescence amelioration, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
14. Park J, Park JT (2024) ε-viniferin, which selectively kills cells to prevent senescence, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
15. Yoon JH, Park JT (2024) Identification of the anti-senescence properties mechanism of vitisin B, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
16. Lee YJ, Park JT (2024) Mitochondrial amelioration and anti-aging effects of KB3409, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
17. Lee YJ, Park JT (2024) Senomorphiceffect of dehydroacteosideas an anti-senescence, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
18. Kim DY, Park JT (2024) Synergistic effect of p38 MAPK and BRAF inhibitor at senescence amelioration (Synergy effect of SB590885 and SB203580), International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회
19. So B, Park JT (2024) Identification of anti–senescence mechanism of isoshaftoside targeting Rac2 protein, International Conference 2024, May 28 ~ May 31, 2024, 생화학분자생물학회

[2023]

1. Song ES, Park JT (2023) Discovery of new endogenous promoters in CHO cells through promoter trapping, 15th International Symposium on Natural Sciences, October 30th ~ October 31th, 2023, Research Institute of Basic Sciences, Incheon National University
2. Lee YH, Park JT (2023) Identification of senescence rejuvenation and metabolic reprogramming by alpha–enolase regulation. 15th International Symposium on Natural Sciences, October 30th ~ October 31th, 2023, Research Institute of Basic Sciences, INU
3. Kuk MU, Park JT (2023) The ROSA26 BAC endogenous promoter enhances the synthesis of recombinant proteins, 15th International Symposium on Natural Sciences, October 30th~ 31th, 2023, Research Institute of Basic Sciences, INU
4. Kuk MU, Park JT (2023) Minimization of human β-interferon MARs in recombinant protein production systems, 15th International Symposium on Natural Sciences, October 30th~ 31th, 2023, Research Institute of Basic Sciences, INU
5. Kuk MU, Park JT (2023) Mitochondrial dysfunction caused by the 3C protease of coxsackievirus B3 in HeLa cell, 15th International Symposium on Natural Sciences, October 30th~ 31th, 2023, Research Institute of Basic Sciences, INU
6. Lee YH, Kuk MU, Park J, Ahn SK, Park JT (2023) Identification of senescence rejuvenation and metabolic reprogramming by alpha–enolase regulation. The 40th Spring Conference of the Korean Society for Gerontology & Korea-Japan Joint Symposium, July 13 ~ July 15, 2023, The Korean Society For Gerontology.
7. Lee YH, Ahn SK, Park JT (2023) Identification of senescence rejuvenation and metabolic reprogramming by alpha–enolase regulation. International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회
8. Kuk MU, Park JT (2023) The ROSA26 BAC Endogenous Promoter: A Novel Strategy for Optimizing Recombinant Protein Production Efficiency, International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회
9. Kuk MU, Park JT (2023) Harnessing iMARs for Enhanced Recombinant Protein Expression in Biopharmaceutical and Gene Therapy Applications, International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회
10. Kuk MU, Park JT (2023) Exploiting CVB3 3C Protease Mutants for Therapeutic Intervention of Coxsackievirus B3 Infection, International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회
11. Song ES, Kang KY, Park JT (2023) Natural substances with anticancer activity discovered in fungal extracts, International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회
12. Song ES, Kang KY, Park JT (2023) Increased Protein Productivity Through the Use of the RMCE (Recombinase-Mediated Cassette Exchange) System and P2A, International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회
13. Lee H, Park JT (2023) Discovery of new endogenous promoters in CHO cells through promoter trapping, International Conference 2023, May 10 ~ May 13, 2023, 생화학분자생물학회

[2022]

1. Lee YH, Park JT (2022) Development of cell lines of freshwater fish species and evaluation of ecotoxicity, 제18회 대한 독성 유전·단백체 학회 국제 학술대회, Oct 25th~27th 2022, 대한독성유전·단백체학회
2. Ko G, Park JT (2022) Efficient expression of recombinant protein mammalian system using S/MAR elements. 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
3. Song ES, Park JT (2022) Natural substances with anticancer properties discovered in Polyporus tuberaster mycelium extract, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
4. Song ES, Park JT (2022) Modification of recombinase-mediated cassette exchange (RMCE) system to increase protein productivity, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
5. Lee H, Park JT (2022) Discovery of new signal peptides through gene trapping, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
6. Lee H, Park JT (2022) Finding effective genomic hot spots through gene trapping, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
7. Lee H, Park JT (2022) High expression level protein production through dual promoter construction, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
8. Park JY, Park JT (2022) Improvement of Tol2 transposase system using H2B enabling efficient protein production in CHO cells, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
9. Park JY, Park JT (2022) Restoration of lysosomal and mitochondrial function through MAPK inhibition ameliorates senescence, 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
10. Lee YH, Ahn SK, Park JT (2022) Discovery of anticancer substances in fungal extracts through high throughput screening Anticancer activities in the ethanol extracts of Polyporus. 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
11. Lee YH, Ahn SK, Park JT (2022) Discovery of senomorphic compounds using high-throughput screening. 14th International Symposium on Natural Sciences, October 6th ~ October 7th, 2022, Research Institute of Basic Sciences, Incheon National University
12. Park JY, Park JT (2022) Improvement of Tol2 transposase system using H2B enabling efficient protein production in CHO cells, 2022년도 생화학분자생물학회 춘계 국제학술대회, MAY 23th~26th 2022, 생화학분자생물학회
13. Park JY, Park JT (2022) Reprogramming mitochondrial metabolism through MAPK inhibition improves aging, 2022년도 생화학분자생물학회 춘계 국제학술대회, MAY 23th~26th 2022, 생화학분자생물학회
14. Song ES, Park JT (2022) Increased Protein Productivity Through the Use of the RMCE (Recombinase-Mediated Cassette Exchange) System and P2A, 2022년도 생화학분자생물학회 춘계 국제학술대회, MAY 23th~26th 2022, 생화학분자생물학회
15. Song ES, Park JT (2022) Natural substances with anticancer activity discovered in fungal extracts, 2022년도 생화학분자생물학회 춘계 국제학술대회, MAY 23th~26th 2022, 생화학분자생물학회
16. Lee H, Park JT (2022) Finding effective genomic hot spots through gene trapping, 2022년도 생화학분자생물학회 춘계 국제학술대회, MAY 23th~26th 2022, 생화학분자생물학회
17. Lee H, Park JT (2022) The development of a new hybrid promoter capable of stable protein expression at high levels, 2022년도 생화학분자생물학회 춘계 국제학술대회, MAY 23th~26th 2022, 생화학분자생물학회
18. Lee YH, Ahn SK, Park JT Discovery of anticancer substances in fungal extracts through high throughput screening Anticancer activities in the ethanol extracts of Polyporus. international Conference 2022, May 23rd ~ May 26th, 2022, KSBMB

[2021]

1. Song ES, Park JT (2021) Applying the 2A system to the recombinase-mediated cassette exchange (RMCE) system to increase protein productivity, 2021년도 한국분자∙세포생물학회 추계학술대회, NOV 03th~05th 2021, 한국분자∙세포생물학회
2. JOO JH, Park JT (2021) Tol2 transposase system with ELS mutation to increase protein productivity, 2021년도 한국분자∙세포생물학회 추계학술대회, NOV 03th~05th 2021, 한국분자∙세포생물학회
3. Lee H, Park JT (2021) Finding Effective Genomic Hot Spots Through Gene Trapping, 2021년도 한국분자∙세포생물학회 추계학술대회, NOV 03th~05th 2021, 한국분자∙세포생물학회
4. JOO JH, Park JT (2021) Tol2 transposase system with ELS mutation to increase protein productivity, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
5. Kuk MU, Park JT (2021) BAC based antibody expression platform using Tol2 transposon in CHO cells, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
6. Kuk MU, Park JT (2021) Metabolic reprogramming from oxidative phosphorylation to glycolysis is induced by Coxsackievirus B3 in Hela cells, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
7. Kuk MU, Park JT (2021) Mitochondrial metabolic reprogramming via AKT inhibition ameliorates senescence, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
8. Kuk MU, Park JT (2021) Superior secretion gene trapping in Chinese hamster ovary cell line, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
9. Lee H, Park JT (2021) Finding effective genomic hot spots through gene trapping, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
10. Lee H, Park JT (2021) Inducing a Protein with high expression level through the construction of a new hybrid promoter, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
11. Song ES, Park JT (2021) Modification of recombinase-mediated cassette exchange (RMCE) system to increase protein productivity, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
12. Park JY, Park JT (2021) Improved Tol2 transposase system with increased transposase number enabling efficient protein production in CHO cells, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
13. Park JY, Park JT (2021) Improvement of Tol2 transposase system using H2B enabling efficient protein production in CHO cells, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
14. Lee YH, Park JT (2021) Discovery of anticancer substances in fungal extracts through high throughput screening, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
15. Lee YH, Park JT (2021) Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
16. Lee YH, Park JT (2021) Improved productivity of Sleeping Beauty transposon in CHO cell, 13th International Symposium on Natural Sciences, October 6th 2021, Research Institute of Basic Sciences, Incheon National University
17. Lee H, Park JT (2021) Finding effective genomic hot spots through gene trapping and constructing new cell lines, 2021년도 생화학분자생물학회 춘계 국제학술대회, MAY 25th~27th 2021, 생화학분자생물학회
18. Song ES, Park JT (2021) Modification of recombinase-mediated cassette exchange (RMCE) system to increase protein productivity, 2021년도 생화학분자생물학회 춘계 국제학술대회, MAY 25th~27th 2021, 생화학분자생물학회
19. Park JY, Park JT (2021) Improving the ability of Tol2 transposase in CHO cells, 2021년도 생화학분자생물학회 춘계 국제학술대회, MAY 25th~MAY 27th 2021, 생화학분자생물학회
20. Lee YH, Park JT (2021) Improved productivity of Sleeping Beauty transposon in CHO cell, 2021년도 생화학분자생물학회 춘계 국제학술대회, MAY 25th~27th 2021, 생화학분자생물학회
21. Lee YH, Choi D, Byun Y, Park JT (2021) Chemical screening identifies the regulation of mitochondrial cristae formation as a target for alleviating senescence, 2021년도 생화학분자생물학회 춘계 국제학술대회, MAY 25th~27th 2021, 생화학분자생물학회

[2020]

1. Lee YH, Park JT (2020) Improved productivity of Sleeping Beauty transposon in CHO cell, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
2. Hwang SY, Kuk MU, Kim JW, Park JT (2020) ATM mediated-p53 signaling pathway forms a novel axis for senescence control, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
3. Hwang SY, Kuk MU, Kim JW, Park JT (2020) Improved Tol2 transposon-based system for efficient protein production, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
4. Kim JW, Park JT (2020) Mitochondrial metabolic reprograming via AKT inhibition ameliorates senescence, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
5. Kim JW, Park JT (2020) Cre-Lox based RMCE for efficient gene-of-interest exchange in CHO cells, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
6. Kuk MU, Park JT (2020) BAC based antibody expression platform using Tol2 transposon in CHO cells, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
7. Kuk MU, Park JT (2020) Metabolic reprogramming from oxidative phosphorylation to glycolysis is induced by Coxsackievirus B3 in Hela cells, 12th International Symposium on Natural Sciences, October 9th 2020, Research Institute of Basic Sciences, Incheon National University
8. Lee YH, Park JT (2020) Improved productivity of Sleeping Beauty transposon in CHO cell, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회
9. Hwang SY, Kuk MU, Kim JW, Park JT (2020) ATM mediated-p53 signaling pathway forms a novel axis for senescence control, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회
10. Hwang SY, Kuk MU, Kim JW, Park JT (2020) Improved Tol2 transposon-based system for efficient protein production, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회
11. Kim JW, Park JT (2020) Mitochondrial metabolic reprograming via AKT inhibition ameliorates senescence, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회
12. Kim JW, Park JT (2020) Cre-Lox based RMCE for efficient gene-of-interest exchange in CHO cells, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회
13. Kuk MU, Park JT (2020) BAC based antibody expression platform using Tol2 transposon in CHO cells, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회
14. Kuk MU, Park JT (2020) Metabolic reprogramming from oxidative phosphorylation to glycolysis is induced by Coxsackievirus B3 in Hela cells, 2020년도 생화학분자생물학회 추계 국제학술대회, September 21th~23th 2020, 생화학분자생물학회

[2019]

1. Kuk MU, Park JT (2019) Antibody expression platform using Tol2 transposon in CHO cells, 11th International Symposium on Natural Sciences, October 9th~11th 2019, Research Institute of Basic Sciences, Incheon National University
2. Kuk MU, Park JT (2019) BAC Recombineering Gain and Loss method enable it to finish within one week, 11th International Symposium on Natural Sciences, October 9th~11th 2019, Research Institute of Basic Sciences, Incheon National University
3. Kim JW, Kuk MU, Park JT (2019) A crucial role of B-RAF for alleviation of senescence-associated phenotypes, 11th International Symposium on Natural Sciences, October 9th~11th 2019, Research Institute of Basic Sciences, Incheon National University
4. Kim JW, Park JT (2019) Next Generation Vector Platform for Therapeutic Protein Production; RMCE-mediated site specific integration, 11th International Symposium on Natural Sciences, October 9th~11th 2019, Research Institute of Basic Sciences, Incheon National University
5. Kuk MU, Park JT (2019) Antibody expression platform using Tol2 transposon in CHO cells, 2019년도 생화학분자생물학회 춘계 국제학술대회, June 02th~05th 2019, 생화학분자생물학회
6. Kuk MU, Park JT (2019) BAC Recombineering Gain and Loss method enable it to finish within one week, 2019년도 생화학분자생물학회 춘계 국제학술대회, June 02th~05th 2019, 생화학분자생물학회
7. Kim JW, Kuk MU, Park JT (2019) A crucial role of B-RAF for alleviation of senescence-associated phenotypes, 2019년도 생화학분자생물학회 춘계 국제학술대회, June 02th~05th 2019, 생화학분자생물학회
8. Kim JW, Park JT (2019) Next Generation Vector Platform for Therapeutic Protein Production; RMCE-mediated site specific integration, 2019년도 생화학분자생물학회 춘계 국제학술대회, June 02th~05th 2019, 생화학분자생물학회

[2018]

1. Kuk MU, Park JT (2018) A crucial role of B-Raf for alleviation of senescence-associated phenotype, 11th International Symposium on Natural Sciences, October 11th 2018, Research Institute of Basic Sciences, Incheon National University
2. Park JT (2018) A Next Generation Vector Platform for Therapeutic Protein Production; BAC-based expression and RMCE-mediated site specific integration, 2018년도 Antibody Society Korea Summer Workshop, July 05th~07th 2018, Antibody Society Korea

Incheon

National

University

Protein

Engineering

Lab

국내 / 연구실 소개 - 생화학분자생물학회

Research Field

Protein Engineering

Aging

Cancer Cell Biology

Professor

2004

Johns Hopkins School of Medicine

2013

Samsung Advanced Institute of Technology

2016

Samsung Bioepis

2017

Incheon National University

Current Member

Combined Master's and Ph.D. Degree Student: Jiho Park CV: [pdf] ​Project: 1) Skin rejuvenation project (KB3407, KB2779)

Master Degree Student: Yu Jin Lee CV: [pdf] ​Project: 1) Skin rejuvenation project

Master Degree Student: Minseon Kim CV: [pdf] ​Project: 1) Skin rejuvenation project 2) Ecotoxicity Project

Undergraduate Student: JIHYUN SONG CV: [pdf] ​Project: 1) Skin rejuvenation project

Undergraduate Student: Se Hui Lim CV: [pdf] ​Project: 1) Skin rejuvenation project

Undergraduate Student: Hanna Lee CV: ​Project: 1) Skin rejuvenation project

2026 송은선 석사 입사 축하

2026 Lab dinner at 배다리

2025 Lab member

2025 이윤행 박사 입사 축하

2025 이하늘 석사 입사 축하

2025 김두열 석사 입사 축하

2025 국명욱 박사 입사 축하

2025 소병현 석사 입사 축하

2024 Lab Homecoming day

2023 Graduation Party (Aug)

2023 Graduation Party (Feb)

2022 Lab Homecoming day

2021 KSBMB (생화학분자생물학회 국제학술대회) Best Research Award

https://www.ksbmb.or.kr/html/?pmode=webzine&smode=viewDetail&id=202106&menu=907&seq=35294

2021 Teacher's day

2019 March

2020 Graduation Party

2019 Christmas Party

2018 ASK summer workshop

2018 Christmas Party

Previous Member

Number of post-doc graduates: 2

Number of Ph.D. degree graduates: 4

Number of Master degree graduates: 10

Jae Won Kim Master Degree: Feb 2021 CV: [pdf] Current position: (주)디엑스앤브이엑스(Dx&Vx)

Soo Young Hwang Master Degree: Feb 2021 CV: [pdf] Current position: (주)바이오노트

Eun Seon Song Master Degree: Feb 2024 CV: [pdf] ​Current position: 한국과학기술연구원(KIST) 정규직 연구원

HANEUR LEE Master Degree: Aug 2023 CV: [pdf] Current position: 인천광역시 보건연구사

Yoon Haeng Lee Master Degree: Feb 2022 Ph.D. Degree: Feb 2024 Post doc: Nov 2025 CV: [pdf] Current position: 대웅제약 선임연구원

Duyeol Kim Master Degree: Feb 2026 CV: [pdf] Current position: (주)라피끄 연구원

Ki Sik Shin Ph.D. Degree: Feb 2022 CV: ​Current position: 국립환경과학원 연구관

Moon Kyoung So Ph.D. Degree: Aug 2024 CV: [pdf] ​Current position: Thermo Fisher Scientific 이사

Byeonghyeon So Master Degree: Feb 2026 CV: [pdf] ​Current position: 한국화학융합시험연구원 연구원

Ji Yun Park Master Degree: Feb 2023 CV: [pdf] Current Position: (주)SCM생명과학

Myeong Uk Kuk Master Degree: Feb 2020 Ph.D. Degree: Feb 2024 Post doc: Dec 2024 CV: [pdf] Current position: 엣진(Edgene) 선임연구원

Jee hee Yoon Master Degree: Aug 2026 CV: [pdf] ​​Current position: ​취업 준비 중

Publication

Patent

Courses

Poster Presentation

Combined Master's and Ph.D. Degree Student:
Jiho Park
CV: [pdf]
Project:
1) Skin rejuvenation project
(KB3407, KB2779)

Master Degree Student:
Yu Jin Lee
CV: [pdf]
Project:
1) Skin rejuvenation project

Master Degree Student:
Minseon Kim
CV: [pdf]
Project:
1) Skin rejuvenation project
2) Ecotoxicity Project

Undergraduate Student:
JIHYUN SONG
CV: [pdf]
Project:
1) Skin rejuvenation project

Undergraduate Student:
Se Hui Lim
CV: [pdf]
Project:
1) Skin rejuvenation project

Undergraduate Student:
Hanna Lee
CV:
Project:
1) Skin rejuvenation project

Jae Won Kim
Master Degree: Feb 2021
CV: [pdf]
Current position:
(주)디엑스앤브이엑스(Dx&Vx)

Soo Young Hwang
Master Degree: Feb 2021
CV: [pdf]
Current position:
(주)바이오노트

Eun Seon Song
Master Degree: Feb 2024
CV: [pdf]
Current position:
한국과학기술연구원(KIST)
정규직 연구원

HANEUR LEE
Master Degree: Aug 2023
CV: [pdf]
Current position:
인천광역시 보건연구사

Yoon Haeng Lee
Master Degree: Feb 2022
Ph.D. Degree: Feb 2024
Post doc: Nov 2025
CV: [pdf]
Current position:
대웅제약 선임연구원

Duyeol Kim
Master Degree: Feb 2026
CV: [pdf]
Current position:
(주)라피끄 연구원

Ki Sik Shin
Ph.D. Degree: Feb 2022
CV:
Current position:
국립환경과학원 연구관

Moon Kyoung So
Ph.D. Degree: Aug 2024
CV: [pdf]
Current position:
Thermo Fisher Scientific 이사

Byeonghyeon So
Master Degree: Feb 2026
CV: [pdf]
Current position:
한국화학융합시험연구원
연구원

Ji Yun Park
Master Degree: Feb 2023
CV: [pdf]
Current Position:
(주)SCM생명과학

Myeong Uk Kuk
Master Degree: Feb 2020
Ph.D. Degree: Feb 2024
Post doc: Dec 2024
CV: [pdf]
Current position:
엣진(Edgene) 선임연구원

Jee hee Yoon
Master Degree: Aug 2026
CV: [pdf]
Current position:
취업 준비 중